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GYNOSTEMMA PENTAPHYLLUM LEAF/STEM EXTRACT.

Valuable CAS - / ANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Gynostemma Pentaphyllum Leaf/Stem Extract is a versatile botanical renowned for its multi-faceted benefits, including potent antioxidant and anti-inflammatory actions. It actively supports skin health by enhancing barrier function, boosting hydration, and promoting youthful skin through collagen and glycosaminoglycan (GAGs) stimulation.

Antioxidant Anti-inflammatory Skin-Conditioning Humectant Astringent Collagen Synthesis Support Barrier Strengthening Detoxifying Microcirculation Enhancer Adaptogen

Science

This extract operates as a robust antioxidant, neutralizing free radicals and preventing cellular damage. Its anti-inflammatory properties effectively soothe irritation, while adaptogenic qualities enable the skin to better manage environmental stressors. It enhances microcirculation, optimizing oxygen and nutrient delivery, and assists in detoxification to minimize impurity buildup. Furthermore, it stimulates the production of collagen and glycosaminoglycans (GAGs), fundamental for improving skin elasticity, firmness, and plumpness. It also functions as an astringent to refine pores and an emollient for a softer, smoother complexion.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Commonly dusted

Gynostemma Pentaphyllum extract, when in powder form, exhibits hygroscopic properties, meaning it readily absorbs moisture from the air, which can lead to clotting if not stored appropriately. The inclusion of inert fillers can mitigate this tendency, enhancing handling and formulation stability.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract demonstrates acceptable stability in cosmetic formulations. However, in powder form, it is hygroscopic and may clot, a characteristic that can be managed through proper storage and the strategic incorporation of fillers.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Gynostemma Pentaphyllum Leaf/Stem Extract is generally considered safe for cosmetic application, adhering to European Union safety regulations. While rare individual sensitivities may occur, its profile indicates a low risk of adverse reactions. Oral toxicity studies in rats established a No Observed Adverse Effect Level (NOAEL) at 750 mg/kg for oral extract, with no mortality or abnormalities observed at doses up to 5000 mg/kg single dose or 1000 mg/kg/day for 90 days. The FDA acknowledges 'Gynostemma Pentaphyllum Leaf' with a UNII, but has not provided a specific safety assessment for its cosmetic use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Gynostemma Pentaphyllum Leaf/Stem Extract is a valuable botanical offering comprehensive benefits, including antioxidant protection, anti-inflammatory effects, collagen stimulation, and adaptogenic support for resilient, radiant skin, suitable for all skin types.


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