Science
Mechanism of Action
This botanical extract operates as a potent antioxidant, effectively neutralizing free radicals and protecting dermal cells from environmental oxidative stress, thereby contributing to the delay of cellular aging. Its adaptogenic qualities bolster the skin's capacity to respond to external stressors like pollution, temperature shifts, and fatigue, fostering a balanced and robust complexion. The extract enhances skin barrier function and moisture retention, leading to improved hydration and radiance. Furthermore, it calms visible irritation and redness through anti-inflammatory actions, while stimulating collagen synthesis and the production of glycosaminoglycans (GAGs) to improve skin firmness, elasticity, and reduce the appearance of fine lines and wrinkles. It also aids in skin detoxification by promoting microcirculation and may support a healthy skin microbiome through its antibacterial properties.
Research
Clinical Evidence
Medium confidence0.45%
Key findings
- 01 An optimum concentration of 0.45% (4.5 mg/mL) Gynostemma pentaphyllum extract significantly prolonged the viability of mouse dermal fibroblasts damaged by UVC light-induced oxidative stress, showing potential benefits on dermal cell aging.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract demonstrates good water absorption and moisturizing capabilities, maintaining stability for at least 24 hours. It is noted that an acidic pH range, specifically pH 3 to 5, is advantageous for the initial extraction process of the Gynostemma pentaphyllum leaves.
Safety
Safety Profile
Gynostemma pentaphyllum extract possesses a favorable safety profile for cosmetic use, with scientific data indicating rare instances of adverse reactions. While generally well-tolerated, a patch test is advised for individuals with known sensitivities to plants or herbs. Preclinical studies in rats showed no mortality or toxic symptoms, and in vitro cytotoxicity tests maintained over 80% cell viability at concentrations up to 0.22%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Gynostemma pentaphyllum extract is a valuable, multifunctional botanical active that offers significant antioxidant, adaptogenic, and anti-aging benefits with a favorable safety profile across all skin types.
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