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Moumoujus

GYMNEMA SYLVESTRE LEAF POWDER.

Valuable / SKIN CONDITIONING

Gymnema Sylvestre Leaf Powder is a multifaceted botanical extract recognized for its cellular energizing, antioxidant, and anti-inflammatory properties. It supports collagen synthesis, enhances moisture retention, and promotes a brighter, more even skin tone, making it beneficial for comprehensive skin rejuvenation.

Summary

Antioxidant Soothing Antimicrobial/antibacterial Astringent Collagen Booster Anti-aging Brightening Exfoliating Moisture Retention Cellular Energizer Anti-inflammatory

Science

Mechanism of Action

This ingredient acts as a powerful antioxidant, protecting skin cells from environmental damage. On a cellular level, it significantly boosts ATP synthesis, stimulates cytochrome c oxidase activity, and drives ribose 5-phosphate synthesis, thereby regulating metabolic and energy processes critical for skin vitality. These actions invigorate skin cells, promoting increased collagen production for improved firmness and elasticity, and helping to reduce the visibility of fine lines and wrinkles. Additionally, it aids in reducing melanin formation for a more uniform skin tone, enhances moisture retention, offers gentle exfoliating benefits, and possesses antimicrobial properties that extend to scalp health.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–10%
Optimal

N/A

Key findings

  1. 01 In cosmetic compositions, concentrations between 0.01% and 10% (preferably 0.01% to 5% by dry weight) have demonstrated efficacy in regulating metabolic and energy processes, increasing ATP synthesis, stimulating cytochrome c oxidase activity, and inducing ribose 5-phosphate synthesis in skin cells.
  2. 02 Treatment of cells with Gymnema sylvestre extract at 0.125% and 0.25% concentrations stimulated the synthesis of ribose 5-phosphate within 24 hours.
  3. 03 Triterpenoids derived from an ethanol extract, applied at 50-555 nmol/ear, exhibited marked anti-inflammatory effects against TPA-induced inflammation in a mouse ear edema model, suggesting soothing properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) and Scientific Committee on Consumer Safety (SCCS) have not specifically reviewed Gymnema sylvestre leaf powder for topical cosmetic applications. While oral consumption studies suggest general safety for periods up to 20 months, some individuals reported side effects such as nausea, abdominal discomfort, diarrhea, headaches, and rash. High oral doses (300 and 600 mg/kg BW in rats) showed potential compromise to liver and kidney function, though doses at or below 100 mg/kg BW caused no significant alterations. It is not approved by the FDA as a therapy for any medical condition.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Gymnema Sylvestre Leaf Powder is a valuable botanical for comprehensive skin rejuvenation, offering cellular energy, anti-aging benefits, and broad compatibility across all skin types.

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