Science
Mechanism of Action
This extract actively mitigates oxidative stress by neutralizing Reactive Oxygen Species (ROS) and inhibiting lipid peroxidation, thereby safeguarding cellular integrity. Its anti-inflammatory effects are attributed to key compounds such as beta-sitosterol, specific flavonoids (quercetin, kaempferol), and beta-caryophyllene. Furthermore, in vitro studies have demonstrated its efficacy against various bacteria and fungi, while traditional uses suggest mild emollient and astringent characteristics.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has classified Guazuma Ulmifolia Leaf Extract with 'Insufficient Data' and 'No Reported Uses' under the FDA's Voluntary Cosmetics Reporting Program, indicating a lack of comprehensive safety assessment for cosmetic applications. General studies on the plant (often bark for internal use) note potential uterine stimulant activity, advising avoidance during pregnancy. It may also possess hypotensive properties, potentially lowering blood pressure. The leaves contain a minor amount of caffeine (0.14%), which should be considered for individuals with caffeine sensitivity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While Guazuma Ulmifolia Leaf Extract demonstrates promising in vitro antioxidant, anti-inflammatory, and antimicrobial activities, its classification by CIR as 'Insufficient Data' necessitates further rigorous safety and efficacy testing before widespread cosmetic application.
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