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GUAIACOL PHENYLACETATE.

Avoid CAS 4112-89-4 / PERFUMING

Guaiacol Phenylacetate is an aromatic ester primarily valued for its distinct aromatic profile and function as a perfuming agent. Derived from Guaiacol, which is known for its aromatic, antioxidant, and antiseptic attributes, this ingredient imparts scent rather than direct skin benefits.

perfuming

Science

As an aromatic ester, Guaiacol Phenylacetate primarily functions to provide a perfuming effect within formulations. While its parent compound, Guaiacol, offers antioxidant and antiseptic properties that can aid in formulation stability, direct therapeutic mechanisms of Guaiacol Phenylacetate on skin are not currently established.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

For optimal stability, store in a cool, dry place within tightly sealed containers, protected from both heat and light.


Safety

CIR Status
Not reviewed
Sensitization risk High

Guaiacol Phenylacetate is classified as an irritant ('Xi') and has been noted to be irritating to the eyes, respiratory system, and skin (R 36/37/38). Although the FDA recognizes it as Generally Recognized As Safe (GRAS) for use as a flavoring agent and it is recommended up to 3.0000% in fragrance concentrates, its irritant profile warrants significant caution for topical skin applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its high potential for irritation and the absence of demonstrated direct benefits for skin health, Guaiacol Phenylacetate is not recommended for inclusion in precision skincare formulations.


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