Science
Mechanism of Action
This fermented filtrate optimizes the natural properties of its botanical constituents. Grifola frondosa (Maitake) is believed to provide potent antioxidant protection, reduce inflammation by modulating MAPK signaling pathways and decreasing pro-inflammatory cytokines, and contribute to skin brightening through tyrosinase inhibition. Citrus Unshiu Peel further supports skin radiance by inhibiting melanin production via tyrosinase and offers additional antioxidant defense against environmental stressors. Rice Seed and Carthamus Tinctorius Flower are thought to add conditioning and potentially soothing attributes. The fermentation process enhances the bioavailability and efficacy of these ingredients, potentially yielding novel beneficial compounds for superior interaction within the skin matrix.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Grifola frondosa (Maitake) extract has demonstrated antioxidant activity, inhibited skin fibroblastic inflammation and cytotoxicity, and ameliorated atopic dermatitis-like skin lesions in scientific studies. Its anti-inflammatory effects are attributed to suppressing MAPK signaling pathways and reducing pro-inflammatory cytokines.
- 02 Extracts of Grifola frondosa have been linked to skin whitening properties through their ability to inhibit tyrosinase activity.
- 03 Citrus Unshiu Peel Extract shows promising results in vitro and in animal studies for inhibiting tyrosinase, a key enzyme regulating melanin production, thereby promoting skin brightening. It also contains antioxidant components that may protect skin from UV damage.
Transparency
Dusting Analysis
The Formula
Formulation
Synergies
- Fermentation generally enhances the bioavailability and efficacy of botanical ingredients, potentially creating new beneficial compounds.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed this complex fermented filtrate. However, individual components have been assessed: Grifola frondosa extract is considered 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', and 'Irritant Free' by SkinSAFE. CIR has reviewed Citrus flower- and leaf-derived ingredients, concluding they are safe for use in cosmetics when formulated to be non-sensitizing and non-irritating, provided leave-on products do not contain more than 0.0015% (15 ppm) 5-methoxypsoralen (5-MOP). CIR has also assessed yeast-derived ingredients, concluding many are safe if derived from yeast species with established dermal sensitization and food use status, though some had insufficient data. Due to the presence of Citrus components and the lack of specific review for the complex filtrate, careful formulation is advised to mitigate potential sensitization risks.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional fermented filtrate offers significant antioxidant protection, anti-inflammatory benefits, and skin brightening effects, making it a valuable addition to diverse skincare formulations for enhanced skin health.
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References
Sources