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GRIFOLA FRONDOSA/OPHIOGLOSSUM VULGATUM EXTRACT FERMENT FILTRATE.

Insufficient Data / SKIN CONDITIONING

This innovative ingredient is a ferment filtrate derived from Grifola Frondosa mushroom and Ophioglossum Vulgatum plant. It functions as a multifaceted skin conditioning agent, offering antioxidant, humectant, and anti-inflammatory properties to promote overall skin health and resilience.

skin-conditioning agent antioxidant humectant anti-inflammatory skin brightening collagen booster wound healing

Science

The ferment filtrate leverages the distinct biological activities of its individual botanical components. Grifola Frondosa contributes anti-inflammatory properties by inhibiting MAPK signaling pathways and suppressing pro-inflammatory cytokines, which may alleviate symptoms of inflammatory skin conditions. It also demonstrates significant antioxidant activity, helps reduce hyperpigmentation by inhibiting tyrosinase, and supports skin regeneration through promoting wound healing and collagen biosynthesis. Ophioglossum Vulgatum further enhances antioxidant defense by scavenging free radicals and provides additional anti-inflammatory effects by regulating Nrf2/HO-1/COX2 and TLR4/MYD88 signaling pathways. Moreover, it stimulates HaCaT cell proliferation and migration, upregulating collagen type I alpha 1 chain (COL1A1) and fibronectin 1 (FN1) via the PI3K/AKT/GSK3-β pathway, thereby supporting skin structure and repair.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed this combined Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate. While some yeast-derived ingredients have been reviewed, explicit safety data for this particular complex is not listed. Toxicity data (oral, parenteral, dermal, inhalation) for similar ferment filtrates are noted as undetermined by The Good Scents Company.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

This ingredient exhibits promising multi-functional benefits based on the established properties of its individual botanical components, yet comprehensive clinical efficacy and safety data for the combined ferment filtrate are currently not available.


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