Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

GRIFOLA FRONDOSA MYCELIUM/ARENARIA KANSUENSIS EXTRACT FERMENT FILTRATE.

Insufficient Data / ANTIOXIDANT

This advanced ingredient combines Grifola frondosa mycelium with Arenaria kansuensis extract through a fermentation process, yielding a potent bioactive filtrate. It offers a spectrum of benefits, including robust antioxidant and anti-inflammatory actions, alongside promoting collagen synthesis and cell regeneration. The ingredient further contributes to potential skin brightening and deep hydration.

Summary

Antioxidant Anti-inflammatory Collagen Booster Cell Proliferant Brightening Hydrating Skin Conditioning Wound Healing Anti-aging

Science

Mechanism of Action

The primary action of this ferment filtrate stems from its Grifola frondosa component, which functions as a robust antioxidant, actively neutralizing detrimental oxidative stress. Its anti-inflammatory capabilities are evidenced by its ability to block inflammasome-mediated caspase-1 activation, thereby reducing IL-1β protein secretion, and by interfering with the p38 and ERK MAPK signaling pathways in keratinocytes to suppress pro-inflammatory cytokines. Furthermore, it stimulates collagen biosynthesis and enhances cellular proliferation, contributing to skin rejuvenation. The ingredient also demonstrates an inhibitory effect on melanogenesis, suggesting a brightening potential, while the presence of beta-glucans supports hydration, wound healing, and overall anti-aging benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibition of inflammation in skin fibroblasts, specifically blocking Bisphenol A (BPA)-triggered responses by suppressing inflammasome-mediated caspase-1 activation and reducing IL-1β protein secretion.
  2. 02 Demonstrated antioxidative activity, stimulation of collagen biosynthesis, promotion of cellular proliferation, and inhibition of melanogenesis, observed without significant cytotoxicity.
  3. 03 Alleviation of atopic dermatitis-like symptoms in a murine model through suppression of Th1, Th2, Th17, and Th22 immune responses in skin and spleen, and inhibition of inflammatory cytokine production in keratinocytes via MAPK pathway activation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

Direct safety assessments by the CIR Expert Panel or SCCS for this precise fermented extract are currently unavailable. While Grifola frondosa (Maitake) is an edible mushroom known in traditional Chinese medicine and is generally considered safe for consumption, and some broader yeast-derived ingredients have been reviewed by CIR, explicit dermal safety data for this specific complex ingredient is currently insufficient for a comprehensive evaluation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ferment filtrate presents significant potential for anti-aging, anti-inflammatory, and brightening applications, though further specific safety and optimal concentration data are required for a definitive rating.

Related

Similar Ingredients

Finding similar ingredients…