Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

GRIFOLA FRONDOSA/ILEX PARAGUARIENSIS LEAF EXTRACT FERMENT FILTRATE.

Insufficient Data / ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

This innovative ferment filtrate combines the well-documented benefits of Grifola Frondosa (Maitake mushroom) and Ilex Paraguariensis (Yerba Mate) leaf extracts. Through fermentation, the bioavailability and potency of beneficial compounds are enhanced, offering a multifaceted approach to skin health, including antioxidant, anti-inflammatory, and brightening properties.

Summary

Antioxidant Humectant Skin Conditioning Skin Brightening Anti-inflammatory Antimicrobial Anti-aging

Science

Mechanism of Action

The ingredient operates through several synergistic pathways. Grifola Frondosa contributes to skin brightening by inhibiting tyrosinase, thereby reducing melanin formation. It also exhibits anti-inflammatory actions by modulating inflammatory cytokines and chemokines, potentially through p38 and ERK MAPK signaling pathways, offering relief for inflammatory conditions. Both Grifola Frondosa and Ilex Paraguariensis provide robust antioxidant defense, neutralizing free radicals with polyphenols, flavonoids (e.g., quercetin, rutin), and xanthines. Ilex Paraguariensis further supports anti-aging by preventing skin epithelium protein damage and offers skin conditioning, potentially forming a protective layer. Additionally, Ilex Paraguariensis extracts possess antimicrobial and antifungal properties, including activity against *Malassezia furfur*. Fermentation concentrates and optimizes these compounds, enhancing their effectiveness and skin penetration.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data indicates this ingredient is commonly used at sub-efficacious concentrations. However, established clinical efficacy data for the combined ferment filtrate is not yet available to define a precise dusting threshold.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While the specific stability of the combined ferment filtrate is not detailed, individual Ilex Paraguariensis extracts show good stability of key compounds like chlorogenic acids, flavonoids, and methylxanthines during simulated digestion. Its stability across a pH range of 2 to 7 has also been observed, suggesting robust formulation potential within typical cosmetic pH ranges.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments for this combined ferment filtrate by regulatory bodies such as CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) are not available. However, individual Ilex Paraguariensis leaf extract has demonstrated low toxicity in certain assays.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ferment filtrate shows significant theoretical promise for antioxidant, anti-inflammatory, and brightening effects based on its components, but specific clinical data for the combined ingredient is currently limited, warranting further research.

Related

Similar Ingredients

Finding similar ingredients…