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GNAPHALIUM LEONTOPODIUM FLOWER/LEAF/STEM WATER.

Valuable CAS 223749-06-2 / SKIN CONDITIONING

GNAPHALIUM LEONTOPODIUM FLOWER/LEAF/STEM WATER, commonly known as Edelweiss extract, is a multi-functional botanical ingredient celebrated for its robust protective and restorative properties. Rich in antioxidants and anti-inflammatory compounds, it defends skin against environmental aggressors while supporting barrier integrity and promoting cellular rejuvenation. This extract is highly valued for its ability to enhance skin hydration, reduce signs of aging, and soothe sensitivity across all skin types.

Skin conditioning Antioxidant Anti-inflammatory Barrier support Hydrating Anti-aging Antimicrobial UV protection Skin brightening Collagen booster

Science

This botanical water exerts its benefits through a rich profile of active compounds, including leontopodic acid, isochlorogenic acid, flavonoids, and phenolic acids. It acts as a potent antioxidant, neutralizing free radicals and mitigating oxidative stress. Concurrently, it reduces inflammation by suppressing markers such as COX-2 and iNOS, and fortifies the skin barrier by stimulating keratin 15 and maintaining moisture balance. The extract also contributes to anti-aging by inhibiting collagen-degrading enzymes like MMP-2, thereby promoting collagen synthesis and reducing wrinkle depth. Furthermore, it offers antimicrobial protection, helps shield against UV damage, and aids in reducing hyperpigmentation for a brighter complexion.


Research

High confidence
Effective range 0.001–10%
Optimal

N/A

Key findings

  1. 01 Studies indicate that a concentration range of 0.5% to 3% is most frequently preferred for optimizing skin barrier function, offering protective, strengthening, and regenerative benefits [10].
  2. 02 For boosting antioxidant defenses and enhancing hydration, concentrations between 3% and 5% are suggested [2].
  3. 03 Efficacy against UVB+A induced damage and barrier modulation was assessed using a 5 wt-% (dry residue) concentration in reconstructed human epidermises [10].

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient is typically prepared using cold processes to preserve its potency, as heat can diminish its effectiveness. Storage in a closed container in a dry, room-temperature environment is recommended, with refrigeration post-opening suggested to extend shelf life. Common preservatives like citric acid, sodium benzoate, and potassium sorbate are compatible and often included in formulations [2, 16, 17].


Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Board has not yet evaluated Edelweiss extract. However, topical application is generally considered safe with no notable side effects reported. The Environmental Working Group (EWG) rates its overall hazard as 1 (on a scale of 1-10, 1 being lowest), indicating a very strong safety profile regarding cancer, allergies, and reproductive toxicity. No known hazards for skin or eyes have been identified. While ingestion might lead to diarrhea, this is irrelevant for topical cosmetic use. The FDA recognizes it as a skin conditioning cosmetic ingredient [3, 8, 10, 23].


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

GNAPHALIUM LEONTOPODIUM FLOWER/LEAF/STEM WATER is a valuable multi-functional ingredient offering significant antioxidant, anti-inflammatory, and anti-aging benefits for diverse skin types.


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