Science
Mechanism of Action
This extract primarily functions as a depigmenting agent through its active component, glabridin, which effectively inhibits tyrosinase, an enzyme critical for melanin production. Additionally, liquiritin aids in depigmentation by dispersing existing melanin. Its robust anti-inflammatory properties are attributed to compounds like glycyrrhizin and licochalcone, which visibly reduce redness, irritation, and inflammation. Licochalcone also provides antioxidant defense against environmental stressors, supports collagen synthesis to enhance skin elasticity, and helps balance oil production, proving beneficial for oily skin types.
Research
Clinical Evidence
High confidence10-20% for brightening, 0.5% glabridin for pigmentation inhibition
Key findings
- 01 A 10% licorice extract cream applied twice daily over four weeks demonstrated significant improvements in skin brightness and clarity.
- 02 A serum formulation containing 20% licorice root extract exhibited optimal facial brightening activity, resulting in a notable change in skin color.
- 03 Topical application of 0.5% glabridin, a key active component, effectively inhibited UVB-induced pigmentation in guinea pigs.
Transparency
Dusting Analysis
No data within the research suggests that Glycyrrhiza Glabra Root Juice is commonly 'dusted' or used below an efficacy threshold to mislead consumers about its benefits.
The Formula
Formulation
Stability
The extract demonstrates optimal stability and efficacy within a pH range of 3.5 to 5.5.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that all licorice-derived ingredients, including Glycyrrhiza Glabra Root Juice, are safe for use in cosmetics, having been found non-dermal irritants, non-sensitizers, and non-mutagenic. The FDA lists Licorice (Glycyrrhiza glabra) as Generally Recognized as Safe (GRAS) for direct food substances. Patch testing is advised for individuals with exceptionally sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Glycyrrhiza Glabra Root Juice is a highly valuable ingredient, offering precise depigmenting, anti-inflammatory, and antioxidant actions, making it well-suited for a wide range of skin types and concerns without significant irritancy or comedogenicity risk.
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