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Moumoujus

GLYCYRRHIZA GLABRA ROOT EXTRACT.

Essential CAS 84775-66-6 / BLEACHING, PERFUMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SMOOTHING, SOOTHING

Glycyrrhiza Glabra Root Extract, derived from licorice, is a multi-functional botanical renowned for its skin brightening, soothing, and antioxidant properties. It effectively targets hyperpigmentation while calming irritated skin and offering protection against environmental stressors.

Summary

Antioxidant Skin-soothing Skin brightening Anti-acne Emollient

Science

Mechanism of Action

This extract acts through key active compounds like glabridin, liquiritin, glycyrrhizin, and licochalcone A. Glabridin and liquiritin inhibit the enzyme tyrosinase, crucial for melanin production, thereby reducing hyperpigmentation. Glycyrrhizin and licochalcone A provide potent anti-inflammatory effects, diminishing skin irritation, while flavonoids and glabridin offer antioxidant protection. Licochalcone A also contributes antimicrobial properties, potentially inhibiting acne-causing bacteria, and the extract generally conditions and smoothes the skin.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibited UVB-caused pigmentation in guinea pigs, highlighting its depigmenting efficacy.
  2. 02 Suppressed tyrosinase activity in cultured B16 murine melanoma cells, indicating its potential for skin lightening.

Transparency

Dusting Analysis

Not commonly dusted

Glycyrrhiza Glabra Root Extract possesses well-researched active compounds, such as glabridin, which have demonstrated efficacy in inhibiting pigmentation at specific concentrations. This data on its potent constituents supports its genuine value rather than suggesting it is merely a 'dusting' ingredient.

The Formula

Formulation

Solubility
Both
Optimal pH 3.5 – 5.5
0 7 14

Stability

The extract maintains optimal stability within a pH range of 3.5 to 5.5. It is available in both water-soluble forms for aqueous products and oil-soluble versions suitable for anhydrous formulations like facial oils and balms.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel concluded that all Licorice-derived ingredients are safe for cosmetic use, showing no evidence of dermal irritation, sensitization, or mutagenicity. The FDA lists Licorice as Generally Recognized As Safe (GRAS) for food consumption. However, chronic topical application, particularly of bioactive flavonoids in skin-lightening or anti-aging formulations, warrants consideration for potential endocrine disruption, sensitization, or prooxidant effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Essential

Glycyrrhiza Glabra Root Extract is an essential ingredient for addressing hyperpigmentation, soothing irritation, and providing antioxidant protection across all skin types.

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