Science
Mechanism of Action
This extract operates through multiple mechanisms to enhance skin health. Its active flavonoids, including pinocembrin and licoflavanone, exert potent antioxidant effects, protecting the skin from environmental stressors. The extract also contributes to anti-inflammatory processes, effectively reducing redness and irritation. Furthermore, while components like glabridin and glycyrrhizin (found in broader licorice extracts) are known to inhibit tyrosinase activity and reduce existing melanin for lightening, Glycyrrhiza Glabra Leaf Extract also shows antimicrobial potential against gram-positive bacteria.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for formulations containing this extract is typically observed within a pH range of 3.5 to 5.5. Glycyrrhizin, a prominent component often found in licorice extracts, demonstrates high stability under thermal processing (100°C - 121°C) at pH levels of 4.5 and 9.5. It is noted that formulations incorporating licorice extract tend to be acidic, which can potentially decrease the viscosity of cream bases.
Safety
Safety Profile
The CIR Expert Panel has concluded that all licorice-derived ingredients are safe for cosmetic application and are not considered dermal irritants or sensitizers. However, for Glycyrrhiza Glabra Leaf Extract specifically, some independent assessments indicate low-moderate concerns for allergies, immunotoxicity, and developmental/reproductive toxicity. There is also cited evidence of 'Human adrenal disruptor' activity and limited 'estrogen disruption' associated with Glycyrrhiza Glabra generally. EU regulations for licorice root extract in skincare suggest a maximum concentration of 2-5%, with reported instances of skin reactions (like redness or itching) being rare within this range.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Glycyrrhiza Glabra Leaf Extract is a valuable addition to skincare, delivering antioxidant, soothing, and potential brightening benefits suitable for all skin types, though further specific clinical studies on the leaf extract at precise concentrations would enhance confidence in its dose-dependent efficacy.
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