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GLYCOSYL TREHALOSE HYDROXYPROPYLTRIMONIUM CHLORIDE.

Valuable CAS - / HAIR CONDITIONING, SKIN CONDITIONING

This advanced ingredient combines the potent hydrating properties of Trehalose with the conditioning benefits of a quaternary ammonium salt. It functions as a humectant and skin barrier stabilizer, offering protection against dehydration, antioxidant effects, and potential UV photoprotection, while also enhancing skin texture.

Summary

Humectant Skin Conditioning Skin Barrier Support Antioxidant Texture Enhancer UV Photoprotection (potential) Anti-photoaging (potential)

Science

Mechanism of Action

Glycosyl Trehalose Hydroxypropyltrimonium Chloride operates through a dual mechanism. The Glycosyl Trehalose component, a disaccharide, acts as a powerful humectant, drawing and retaining moisture within the stratum corneum. It aids in protecting cellular structures from environmental dehydration, thereby strengthening the skin's natural barrier. Furthermore, it exhibits antioxidant capabilities and has been noted for potential UV photoprotection and anti-photoaging effects. The Hydroxypropyltrimonium Chloride portion, a positively charged quaternary ammonium salt, provides conditioning and texture-enhancing properties. It achieves this by forming a lightweight, substantive film and electrostatically binding to the negatively charged surfaces of the skin, promoting a smoother, softer feel.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While general pH stability for this combined ingredient is not explicitly stated, similar guar-based hydroxypropyltrimonium chloride compounds suggest initial dispersion at pH 9.0-10.0. Final formulations are commonly adjusted to a pH range of 6.0-7.0 for optimal hydration benefits and viscosity management.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed the safety of related 'Hydroxypropyltrimonium Chloride' compounds, provided they are used at concentrations below 1% to prevent irritation and sensitization. Concentrations exceeding 1% have been noted to potentially cause irritation, necessitating careful formulation, especially for sensitive skin types. Separately, the Trehalose component, as part of Monosaccharides, Disaccharides, and Related Ingredients, has been concluded to be safe for cosmetic use by the CIR Expert Panel.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Glycosyl Trehalose Hydroxypropyltrimonium Chloride is a valuable multifunctional ingredient for skincare, offering significant hydration, barrier stabilization, and conditioning, provided its concentration is precisely managed at or below 1% to mitigate potential irritation.

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