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GLYCINE MAX LEAF EXTRACT.

Valuable / ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

Glycine Max Leaf Extract is a botanical active renowned for its multifaceted benefits, including potent antioxidant and anti-inflammatory properties. It also shows promise in addressing hyperpigmentation and supporting skin elasticity, making it a versatile ingredient for comprehensive skin health.

Antioxidant Anti-inflammatory Skin Brightening Anti-aging Skin Barrier Support Moisturizing

Science

This extract leverages active components like phenolic acids, flavonoids, and isoflavonoids to deliver its dermatological effects. As a strong antioxidant, it neutralizes harmful free radicals by scavenging peroxyl radicals and reducing ferric iron. Its anti-inflammatory action stems from its ability to significantly reduce the production of inflammatory mediators such as nitric oxide and prostaglandin E2. Furthermore, it may contribute to a more even skin tone by interfering with melanosome transfer, thereby preventing melanin from reaching the skin surface. Broader research on related soybean extracts indicates a capacity to stimulate collagen and elastin synthesis and inhibit elastase, promoting skin firmness and reducing aging signs. A related extract from *Glycine soja* leaves and stems has also demonstrated potential in ameliorating atopic dermatitis symptoms by improving barrier function and reducing inflammation.


Research

Medium confidence
Effective range 0.00625–0.5%
Optimal

N/A

Key findings

  1. 01 In 70% methanol extracts, demonstrated 80% DPPH radical scavenging and 88% reducing power (antioxidant effects), along with up to 86% inhibition of nitric oxide synthesis in stimulated macrophages (anti-inflammatory effects).
  2. 02 Ethanol extracts showed 5–61% radical scavenging activity and ferric-reducing anti-oxidant power in vitro.
  3. 03 Ethanol extracts dose-dependently decreased the production of nitric oxide and prostaglandin E2 in lipopolysaccharide-treated macrophages in vitro, indicating anti-inflammatory effects.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While an explicit optimal pH range for stability is not detailed, the active components are commonly extracted using hydro-alcoholic solvents, suggesting good water solubility. Green soybean powder has demonstrated water solubility ranging from 2.02–8.71%.


Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that 24 of 28 soy-derived ingredients are safe as used in cosmetics. However, Glycine Max Leaf Extract specifically lacked sufficient data for a definitive safety determination for this particular extract. While related ingredients like Glycine Soja Seed Extract are recognized as safe by European cosmetic regulations, direct safety assessment for this specific leaf extract is pending, making specific maximum use concentrations and sensitization risk unknown.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Glycine Max Leaf Extract is a valuable ingredient with robust in vitro antioxidant, anti-inflammatory, and potential anti-aging and brightening benefits, though further human clinical and specific safety data are needed for a comprehensive profile.


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