Science
Mechanism of Action
This extract contains a synergistic blend of polysaccharides, proteins, essential amino acids (including glycine and proline), and natural antioxidants. These compounds collectively promote cellular regeneration, optimize skin hydration by retaining moisture, and protect against oxidative damage, thereby enhancing skin resilience and fortifying its protective barrier.
Research
Clinical Evidence
Medium confidence1.5%
Key findings
- 01 An instrumental assessment demonstrated a statistically significant improvement in skin firmness, increasing by +17.9% after 7 days and +24.5% after 21 days. Additionally, a notable reduction in wrinkle depth was observed, decreasing by -10.7% after 7 days and -27.3% after 21 days.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for Glycine Max Callus Extract is observed within a narrow pH range of 4.9-5.1, particularly when co-formulated with flavonoid compounds. Without flavonoids, aqueous cultures show signs of degradation, including darkening and an increase in pH (to approximately 8) within 14 days, suggesting a preference for slightly acidic conditions for enhanced longevity.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that insufficient data exists to determine the safety of Glycine Max Callus Extract for its intended use in cosmetic formulations. They have requested further critical data, including comprehensive composition, impurity profiles, detailed manufacturing processes, 28-day dermal toxicity assessments, and specific sensitization and irritation studies. While some industry sources suggest low irritancy, this regulatory determination by CIR highlights a significant data gap for a precision brand.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite exhibiting promising clinical results for anti-aging and moisturizing benefits, the lack of comprehensive safety data as determined by the CIR Expert Panel currently renders this ingredient's overall suitability as 'insufficient-data' for precision skincare formulations.
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