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GLYCIDOXYPROPYL POLYSILSESQUIOXANE.

Valuable CAS 68611-45-0 / FILM FORMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Glycidoxypropyl Polysilsesquioxane is a versatile silicone polymer functioning primarily as an emollient and film-forming agent. It is engineered to soften and smooth the skin's surface, while creating a durable, breathable, and often water-resistant barrier. This ingredient enhances product feel and longevity, making it beneficial across various cosmetic applications.

Summary

Emollient Film forming Skin conditioning

Science

Mechanism of Action

This ingredient operates by depositing a continuous, resilient film on the skin. This film not only conditions the skin and improves its texture but also contributes to product performance by resisting wash-off and rub-off, thereby extending wear time. As part of the polysilsesquioxane family, it aids in moisture retention without occluding pores and can impart a subtle soft-focus effect to blur imperfections.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data suggests Glycidoxypropyl Polysilsesquioxane is commonly associated with dusting issues or requires specific dusting thresholds.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Glycidoxypropyl Polysilsesquioxane demonstrates high thermal stability, with reports indicating stability up to approximately 300°C. Its insolubility in water and solubility in organic solvents (e.g., chloroform, toluene, THF), with slight solubility in ethanol, makes it well-suited for anhydrous or oil-based cosmetic formulations. No specific optimal pH range for the stability of the final polymer in cosmetic formulations has been identified.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
4.9%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that polysilsesquioxanes, including Glycidoxypropyl Polysilsesquioxane, are safe for use in cosmetic formulations at concentrations described in current practices. While a related polysilsesquioxane (Polymethylsilsesquioxane) can be used up to 55.2%, this specific ingredient and others are typically used at 4.9% or less. Dermal toxicity studies on broader polysilsesquioxane groups showed non-irritating effects in rabbits at 100% concentration and no genotoxic potential. The precursor molecule, 3-Glycidoxypropyltrimethoxysilane, is classified with potential eye damage and aquatic harm, and mild irritation to skin and eyes, but these concerns do not extend to the final polymer, which is not a known skin sensitizer.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Glycidoxypropyl Polysilsesquioxane is a valuable ingredient, recognized for its safety and broad skin compatibility, effectively enhancing skin feel, product longevity, and subtle imperfection blurring through its film-forming and emollient properties.

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