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GLYCERYL ISOSTEARATE/MYRISTATE.

Valuable CAS 126539-55-7 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Glyceryl Isostearate/Myristate is a multifunctional ester that enhances the sensory experience and stability of cosmetic formulations. It acts as an effective emollient, delivering a smooth skin feel, and as a robust emulsifier and emulsion stabilizer, preventing ingredient separation.

Summary

Skin-conditioning agent Emollient Emulsifying agent Emulsion stabilizer Film former

Science

Mechanism of Action

This ingredient functions primarily as a skin-conditioning agent, forming a light, protective film on the skin's surface to enhance softness and smoothness. Chemically, as an emulsifying agent, it facilitates the uniform blending of oil and water components, crucial for stable formulations. It further stabilizes these emulsions against environmental fluctuations like temperature changes and varying oil levels. Structurally, it is a glyceryl monoester that is metabolized into free fatty acids and glycerol upon application.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Glyceryl Isostearate/Myristate's primary roles are as an emollient, emulsifier, and stabilizer, where its presence is foundational to formulation integrity and sensory attributes rather than a 'hero' active ingredient whose efficacy could be diminished by dusting.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Functions as a robust emulsion stabilizer, preventing oil and liquid component separation. It aids in thickening emulsions and enhances stability against temperature fluctuations and elevated oil content.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel affirmed its safety within the Myristic Acid and its esters group for current cosmetic practices. While a 50% concentration in a guinea pig study showed slight sensitization potential for a component, this is significantly higher than typical cosmetic usage levels. The FDA permits Myristic Acid and other fatty acids in food, further supporting a favorable safety profile. No specific SCCS opinion has been identified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Glyceryl Isostearate/Myristate is a valuable ingredient for enhancing skin conditioning, formulation stability, and sensory texture across a wide range of cosmetic products, deemed safe for typical use.

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