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GLYCERYL CAPRATE.

Valuable CAS 26402-22-2 / SKIN CONDITIONING - EMOLLIENT

Glyceryl Caprate is a versatile, plant-derived ingredient functioning as an emollient, emulsifier, and antimicrobial agent. It is recognized for enhancing skin texture, stabilizing cosmetic formulations, and extending product shelf life through its broad-spectrum antimicrobial activity.

Emollient Emulsifying Antimicrobial Moisturizer Preservative Penetration Enhancer

Science

Glyceryl Caprate improves skin texture by softening, smoothing, and boosting moisture levels. It acts as an antimicrobial preservative by disrupting microbial cell membranes, thereby inhibiting bacterial and fungal growth and enhancing product longevity. Additionally, it stabilizes oil-in-water emulsions as a co-emulsifier, reducing interfacial tension to facilitate mixing. Furthermore, it can function as a penetration enhancer, modulating the stratum corneum's lipid bilayer for improved transdermal delivery of active compounds.


Research

High confidence
Effective range 0.3–5%
Optimal

0.3%

Key findings

  1. 01 Concentrations from 0.5% to 5% are well tolerated by the skin, providing emollient, conditioning, and co-emulsifying benefits.
  2. 02 At 0.3-0.5%, it exhibits effective antimicrobial properties by disrupting microbial cell membranes, inhibiting bacteria and fungi.
  3. 03 A 1-2% concentration significantly boosts preservative system performance, demonstrating robust antimicrobial activity against bacteria and yeast.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 4.5 – 7
0 7 14

Stability

Glyceryl Caprate maintains optimal stability and performance within a pH range of 4.5 to 7.0. It melts above 30°C and can be safely heated up to 80°C. It is compatible with surfactant-based and alcohol-containing formulations and can be incorporated into the water phase of emulsions. For purely aqueous products without alcohol, a solubilizer is necessary. Formulators should note it may slightly reduce emulsion viscosity, recommending preliminary trials.

Synergies

  • Surfactant solutions
  • Alcohol-based products
  • Preservative systems (enhances efficacy)

Conflicts

  • strong oxidizing agents
  • strong alkalies

Safety

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has found Glyceryl Caprate safe for cosmetic use within current practices and concentrations. It is also generally recognized as safe (GRAS) for food applications and is approved for use in the EU, US, and Japan. While generally well-tolerated up to 5%, concentrations exceeding 0.5% in occlusive leave-on products (e.g., balms, face masks) may cause irritation. For facial cleansing oils, a maximum of 0.75% is recommended, and for the eye area, a maximum of 0.3% is advised due to potential localized irritation at higher levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Glyceryl Caprate is a valuable, multi-functional ingredient prized for its emollient, emulsifying, and antimicrobial properties, making it suitable for a wide range of well-tolerated skincare and personal care formulations across all skin types.


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