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Moumoujus

GLYCERYL ARACHIDONATE.

Insufficient Data CAS 35474-99-8 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

Glyceryl Arachidonate is a skin conditioning agent and emollient, recognized for its moisturizing capabilities. It contributes to enhancing skin softness, smoothness, and elasticity while bolstering the skin's natural barrier. Furthermore, it supports skin regeneration, aids in reducing inflammation, and soothes irritated skin.

Summary

Skin Conditioning Emollient Moisturizing Barrier Strengthening Regenerative Anti-inflammatory Soothing Surfactant Emulsifier

Science

Mechanism of Action

This ingredient functions as a potent emollient and skin conditioning agent, improving skin texture and suppleness through deep moisturization. It actively strengthens the skin's lipid barrier, thereby enhancing its protective capabilities against external stressors. Glyceryl Arachidonate promotes natural regenerative processes, mitigates inflammatory responses, and offers soothing relief to irritated skin. Within the skin, it may undergo partial hydrolysis to Arachidonic Acid, and in formulations, it also serves as a surfactant and emulsifier, contributing to emulsion stability.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data indicates this ingredient is commonly 'dusted' or included at ineffective concentrations purely for marketing claims. However, its safety profile warrants careful consideration regarding its inclusion and concentration.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Glyceryl Arachidonate is derived from arachidonic acid, an unsaturated fatty acid, rendering it susceptible to oxidative degradation. Its stability and potential isomerization can be influenced by factors such as temperature, solvent polarity, water activity, and the presence of acid or base impurities in the formulation.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that the available safety data for Glyceryl Arachidonate in cosmetic formulations are insufficient. Further data are required, specifically regarding dermal absorption, immunomodulatory effects, carcinogenicity, photocarcinogenicity, and human irritation, sensitization, and photosensitization. While some generalized sources suggest a positive safety profile, a moderate potential for irritation or allergic reactions has been noted for sensitive individuals and across skin, eyes, or lungs by the EWG Skin Deep database.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Despite its beneficial emollient, moisturizing, and regenerative properties, the 'insufficient data' status from the CIR Expert Panel on its safety profile necessitates caution and further research for widespread use in precision skincare formulations.

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