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GLYCERYL ADIPATE.

Valuable CAS 26699-71-8 / SKIN CONDITIONING - EMOLLIENT

Glyceryl Adipate is a versatile skin conditioning agent and emollient engineered to bolster the skin's natural barrier. It delivers essential lipids to the skin surface, effectively diminishing transepidermal water loss and significantly boosting hydration. This ingredient further contributes to minimizing dryness and offers protective benefits against inflammation.

Skin conditioning Emollient Hydration Skin barrier support Protection against inflammation

Science

Functioning as an emollient and skin conditioning agent, Glyceryl Adipate actively supports and enhances the skin's intrinsic barrier function. It strategically deposits exogenous lipids onto the skin surface, thereby forming a protective film that measurably reduces transepidermal water loss (TEWL) and substantially improves skin hydration. By augmenting the lipid content within the upper epidermal layers, it effectively counteracts degreasing and dryness. Metabolically, it breaks down on the skin into free fatty acids and glycerol, both of which are critical precursors available for the resynthesis of triglycerides, thus reinforcing the skin's natural lipid matrix.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Specific data regarding the 'dusting' potential or common misrepresentation of Glyceryl Adipate concentrations in formulations is not available within the provided research.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific optimal pH and detailed stability for Glyceryl Adipate itself are not explicitly defined, related polymeric forms (Poly(glycerol adipate)) have been observed to be stable at pH 7.4 but demonstrate susceptibility to hydrolytic enzymes. Therefore, careful consideration of the overall formulation's pH and potential enzyme activity is advisable.


Safety

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel has concluded that Glyceryl Adipate, as part of the glyceryl monoester group (excluding Glyceryl Arachidonate), is safe for use as a cosmetic ingredient at current concentrations. This safety assessment was explicitly reaffirmed in a re-review conducted in January 2025. Undiluted forms may cause minor irritation on abraded skin, but at cosmetic concentrations, irritation is generally not expected.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Glyceryl Adipate is a valuable emollient and skin conditioning agent, effectively enhancing barrier function and hydration with a low risk of irritation, making it suitable for a wide range of skin types including dry, normal, and sensitive skin.


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