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GLYCERETH-7 DIISONONANOATE.

Questionable CAS 125804-15-1 / SKIN CONDITIONING - EMOLLIENT, SOLVENT

Glycereth-7 Diisononanoate functions primarily as a skin conditioning agent and a formulation enhancer. It acts as an emollient, providing lipids to enhance the skin barrier and improve hydration while also serving as a solvent to uniformly disperse other cosmetic ingredients.

Emollient Solvent

Science

This ingredient operates as both an emollient and a solvent. In its emollient role, it strengthens the skin's protective barrier by delivering exogenous lipids, thereby boosting hydration levels and potentially reducing inflammation. It achieves this by filling the intercellular spaces between corneocytes, effectively preventing transepidermal water loss and increasing the lipid content within the epidermal layers. As a solvent, Glycereth-7 Diisononanoate facilitates the dissolution or dispersion of various cosmetic components, such as surfactants, oils, pigments, and preservatives, ensuring their even distribution within a product formulation.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Specific optimal pH ranges for Glycereth-7 Diisononanoate are not explicitly documented. However, as an ester, this compound may be susceptible to hydrolysis when exposed to extreme acidic or alkaline pH conditions.

Conflicts

  • Not permitted in certified organic or natural cosmetics due to its ethoxylated nature and potential for carcinogenic impurities (ethylene oxide, 1,4-dioxane).

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has reported insufficient data to conclusively determine the safety of Glycereth-7 Diisononanoate. While referenced in broader assessments of related compounds, a specific safety conclusion for this ingredient is not available. A significant concern arises from its ethoxylated chemical nature, which carries a general risk of contamination with manufacturing impurities such as ethylene oxide (a known carcinogen) and 1,4-dioxane (a carcinogenic by-product). This has led to its classification as 'Muy Dudoso' (Very Doubtful) by some sources, prohibiting its use in certified organic or natural cosmetic products. No specific SCCS opinion or FDA status has been identified.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

While offering emollient and solvent benefits, Glycereth-7 Diisononanoate is considered questionable due to insufficient safety data from the CIR and potential contamination with carcinogenic impurities from its ethoxylation process.


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