Science
Mechanism of Action
This ingredient operates through a three-pronged mechanism within cosmetic formulations. As an emollient, it helps to impart softness and smoothness to the skin, contributing to improved hydration and the formation of a protective barrier to mitigate transepidermal water loss. Its surfactant properties enable it to effectively lower surface tension, thereby facilitating the uniform blending of oil and water components and assisting in the attraction and suspension of oils and dirt for easier rinsing. Furthermore, acting as an emulsifier, Glycereth-6 Triisostearate is instrumental in stabilizing oil-in-water or water-in-oil emulsions, which refines product texture and optimizes spreadability.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Related ethoxylated glycerides, such as Glycereth-6 Cocoate, are typically stable across a moderate pH range. This ingredient exhibits broad compatibility with a wide array of formulation components, including various ionic species, facilitating the creation of stable and uniformly dispersed products.
Safety
Safety Profile
A specific CIR Expert Panel safety assessment for Glycereth-6 Triisostearate has not yet been conducted. However, related ingredients within the broader class of PEGylated alkyl glycerides were concluded safe for rinse-off applications and safe for use up to 10% in leave-on products in a 1999 review. A subsequent 2020 'Glycerin Ethoxylates' report, encompassing this ingredient class, issued a 'Tentative Report with an insufficient conclusion,' explicitly requesting more detailed Human Repeated Insult Patch Test (HRIPT) experimental data. As an ethoxylated compound, there is a general industry concern regarding potential trace contamination with 1,4-dioxane. While the ingredient is cataloged by the FDA under UNII 703EFK0YBW (synonymous with 'glycereth-6 tricocoate'), this serves for identification purposes and does not imply explicit FDA safety approval. No specific SCCS opinion has been issued for Glycereth-6 Triisostearate.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While widely employed across various cosmetic product categories for its versatile emollient, surfactant, and emulsifying properties, specific safety and efficacy data for Glycereth-6 Triisostearate are currently insufficient for a definitive assessment.
Related
Similar Ingredients
Finding similar ingredients…