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Moumoujus

GLUTAMYLAMIDOETHYL INDOLE.

Valuable / SKIN PROTECTING

Glutamylamidoethyl Indole is a multifaceted ingredient that supports comprehensive skin health by promoting nerve growth factor synthesis, protecting against UV-induced damage, and inhibiting nerve degradation. It also enhances collagen production to visibly reduce wrinkles and effectively manages sebum secretion to alleviate acne and shine.

Summary

Skin protecting Anti-aging Wrinkle reduction Sebum control Acne treatment Nerve regeneration

Science

Mechanism of Action

This synthetic dipeptide acts on multiple pathways to fortify skin. It directly protects PC12 neurons from UV damage and stimulates the synthesis of nerve growth factor, crucial for nerve cell regeneration. By inhibiting nerve damage from environmental aggressors, it enhances skin cells' resilience. Furthermore, Glutamylamidoethyl Indole boosts collagen synthesis and strengthens dermal elastic fibers, contributing to a visible reduction in wrinkles. It also actively protects and regenerates skin nervous tissue, thereby combating the signs of aging. An additional benefit is its proven ability to regulate sebum production, which helps mitigate skin shininess and address acne concerns.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Promotes the synthesis of nerve growth factor, protects PC12 neurons from UV radiation, inhibits skin nerve damage from external harmful factors, and strengthens cellular resilience. It increases collagen synthesis to alleviate wrinkles and safeguards skin nervous tissue regeneration to prevent aging.
  2. 02 Demonstrates excellent efficacy in inhibiting sebum secretion, reducing skin shininess, and preventing and treating acne.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest this ingredient is commonly dusted or used at ineffective low percentages.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a synthetic dipeptide, Glutamylamidoethyl Indole is reported to exhibit stability across a range of temperatures and pH conditions.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Glutamylamidoethyl Indole is notably free from a wide array of common irritants and allergens, including dyes, SLS, fragrance, parabens, lanolin, coconut, gluten, soy, and propylene glycol. It is classified as safe for use on delicate skin areas such as the lips and eyelids, and is suitable for teens and babies. INCI Beauty further confirms no safety penalties for this ingredient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A highly versatile ingredient offering significant anti-aging, neuroprotective, and sebum-regulating benefits, suitable for all skin types and delicate areas due to its excellent safety profile.

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