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Moumoujus

GLUCOSYL NARINGIN.

Valuable CAS - / ANTISTATIC, HUMECTANT, SKIN PROTECTING

Glucosyl Naringin is a bio-enhanced flavonoid derivative that significantly boosts skin elasticity and firmness, while fortifying its vital barrier function. This multifaceted ingredient also offers protective benefits against environmental stressors, helping to mitigate inflammation and improve overall skin vitality.

Summary

Antioxidant Skin-Restoring Elasticity Booster Barrier Support Anti-inflammatory Firming Wrinkle Reduction

Science

Mechanism of Action

Glucosyl Naringin (GN) actively promotes the synthesis of elastin and the robust formation of elastic fibers, which are crucial for maintaining youthful skin resilience and reducing visible signs of sagging and wrinkles. It enhances the skin's protective barrier by facilitating the development of the cornified envelope and increasing profilaggrin production, a key precursor to filaggrin that underpins stratum corneum strength and flexibility. Furthermore, GN has demonstrated a capacity to lessen UVB-induced stress and inflammation by protecting cells and increasing their viability. Recent research also suggests that GN may help improve disruptions in circadian rhythms.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–1%
Optimal

1%

Key findings

  1. 01 In in vitro studies, a 1% concentration of Glucosyl Naringin applied to Normal Human Epidermal Keratinocyte (NHEK) cells significantly increased cell viability and reduced the expression of inflammation markers (TNF-α, MMP-9) following UVB exposure. This indicates a protective effect against UVB-induced inflammation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Glucosyl Naringin exhibits remarkably high water solubility, over 6,000 times greater than its aglycone, naringin, facilitating its seamless incorporation into aqueous formulations. For optimal stability, it is recommended to store at room temperature, safeguarding it from direct sunlight, high temperatures, and high humidity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Glucosyl Naringin. However, it is recognized for its gentle, natural profile and holds COSMOS approval. In vitro studies on its aglycone, Naringenin, showed no toxicity to Human Dermal Fibroblasts at tested concentrations. Oral administration of Naringenin at doses ranging from 150 to 900 mg has also been shown to be safe and well-tolerated in healthy adults.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Glucosyl Naringin is a valuable multifunctional ingredient, effectively enhancing skin elasticity and barrier function while providing antioxidant and anti-inflammatory benefits, all with a low risk of irritation.

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