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Moumoujus

GINKGO BILOBA LEAF.

Valuable CAS 90045-36-6 / SKIN CONDITIONING

Ginkgo Biloba Leaf extract is a robust botanical, prized for its multifaceted benefits in precision skincare. This ingredient provides significant antioxidant protection against environmental aggressors, while its anti-inflammatory properties soothe and calm the skin. It also supports vital cellular functions, improving microcirculation and bolstering collagen and elastin production for enhanced skin vitality and resilience.

Summary

Antioxidant Anti-inflammatory Microcirculation Booster Collagen Support Elastin Support Anti-aging Antibacterial Skin Brightening Sebum Regulation Cell Metabolism Stimulant Depigmenting Agent UV Protection Anti-wrinkle

Science

Mechanism of Action

Ginkgo Biloba Leaf extract operates through diverse biochemical pathways to optimize skin health. It acts as a potent scavenger of free radicals, effectively neutralizing damage from UV radiation, pollution, and blue light, thereby preventing premature cellular aging and collagen degradation. The extract demonstrates anti-inflammatory efficacy, reducing redness and soothing irritation, which can benefit conditions such as acne, eczema, and rosacea. Furthermore, it significantly boosts skin microcirculation, facilitating superior delivery of nutrients and oxygen to cells, while aiding in toxin elimination for a brighter, more unified complexion. By stimulating fibroblast activity, it promotes the synthesis of collagen and elastin, leading to improved skin elasticity and a reduction in the appearance of fine lines and wrinkles. Its antibacterial properties help mitigate acne outbreaks and cleanse skin of impurities, and it may also offer mild depigmenting effects through tyrosinase inhibition and some UV protective capacity, with an SPF of up to 4.

Research

Clinical Evidence

Medium confidence
Effective range ≤1.5%
Optimal

1.5%

Key findings

  1. 01 A cream containing Ginkgo Biloba extract demonstrated visually observable anti-wrinkle effects and improvements in skin's overall shape and texture during a two-week human volunteer trial.
  2. 02 Clinical studies of cosmetic formulations incorporating up to 1.5% Ginkgo Biloba Extract (GBEs) reported no adverse reactions, affirming its safety at this concentration.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 7 – 8.5
0 7 14

Stability

Ginkgo Biloba Leaf Extract is reported to be stable and homogeneous in cream formulations. The liquid extract maintains stability within a pH range of 7.0 to 8.5, with peak flavonoid solubility observed at pH 7.8.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
1.5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has determined that certain Ginkgo Biloba leaf-derived ingredients are safe for cosmetic use within specified concentrations, provided they are formulated to be non-sensitizing. There is a noted concern regarding ginkgolic acid impurities, with good manufacturing practices recommended to limit its presence. While sensitization to pure ginkgolic acid has been observed at 0.1% and 1%, an extract containing approximately 0.1% ginkgolic acid did not cause sensitization. Clinical studies confirm no adverse effects when using cosmetic formulations with up to 1.5% Ginkgo Biloba Extract. The FDA generally recognizes it as safe for cosmetic use under CIR guidelines, though its SCCS status remains unknown.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Ginkgo Biloba Leaf is a valuable ingredient, offering broad-spectrum antioxidant protection, anti-aging benefits, and soothing properties suitable for diverse skin concerns.

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