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Ingredient directory

Gelatin/keratin Amino Acids/lysine Hydroxypropyltrimonium Chloride

This complex functions as a multifaceted skin conditioning agent, combining the humectant capabilities of keratin amino acids with the structural support of gelatin and the antistatic properties of a quaternized lysine derivative. It is designed to enhance skin hydration, reinforce the barrier, and improve overall suppleness and elasticity.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Skin conditioning Humectant Antistatic Hair conditioning Barrier reinforcement Elasticity improvement Hydration

Science

The efficacy of this ingredient stems from its composite nature. Keratin amino acids, due to their smaller molecular size, are capable of penetrating the stratum corneum, acting as humectants to draw and retain moisture, thereby reinforcing the skin's natural barrier. This action leads to improved suppleness, reduced dryness, and enhanced elasticity, contributing to potential anti-aging benefits. Gelatin, a highly purified animal protein, further supports the conditioning effect. The Lysine Hydroxypropyltrimonium Chloride component, a quaternary ammonium cation, imparts antistatic properties and, similar to other quaternized proteins, improves the ingredient's substantivity and moisture-binding capacity within cosmetic formulations.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

The keratin amino acids component demonstrates optimal stability within a pH range of 4.5 to 6.5. As a quaternized protein, it is generally compatible with a wide array of cosmetic formulations; however, its cationic nature means it can form large polyanionic complexes when combined with mild primary anionic surfactants.

Conflicts

  • Mild primary anionic surfactants (potential for complex formation)

Safety

CIR Status
Safe with restrictions
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) panel has deemed keratin-derived ingredients, including Keratin Amino Acids, safe under current use practices and concentrations, provided animal-derived raw materials are meticulously screened for infectious pathogens, pesticide residues, and heavy metals. While this specific complex was not individually evaluated, its components align with this assessment. There is a low but present potential for irritation in individuals with sensitive skin, largely attributable to the quaternized compound and protein derivatives. Allergic reactions have been observed in prick tests for Hydrolyzed Keratin but not in standard patch tests.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

GELATIN/KERATIN AMINO ACIDS/LYSINE HYDROXYPROPYLTRIMONIUM CHLORIDE is a valuable multi-component ingredient for precision skincare, effectively boosting hydration, elasticity, and barrier integrity with low irritation potential, though raw material purity and formulation interactions require careful consideration.


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