Science
Mechanism of Action
This extract functions as a robust antioxidant, actively neutralizing free radicals and shielding skin cells from environmental damage, thereby supporting a youthful appearance. Its anti-inflammatory capabilities calm irritation, diminish redness, and enhance overall skin comfort. Furthermore, it exhibits antibacterial and antifungal properties that combat skin impurities, aid in oil regulation, and maintain clear pores, making it particularly beneficial for blemish-prone and oily skin types. It also contributes to a balanced skin microbiome. Key components, such as Alpha-Mangostin, support wound healing processes. For anti-aging, it inhibits enzymes like elastase, collagenase, hyaluronidase, and tyrosinase, and reduces glycation to suppress AGE production, which collectively contribute to improved skin moisture retention and elasticity.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
No data available in the provided research to suggest this ingredient is commonly dusted or to establish a dusting threshold for topical applications.
The Formula
Formulation
Stability
The primary bioactive compounds, such as xanthones, are highly lipophilic and exhibit low solubility in water, which can hinder their topical application and efficacy. They are generally soluble in organic and nonpolar solvents. To enhance stability and improve percutaneous penetration, nanoemulsion-based delivery systems or encapsulation within a cream base are recommended over aqueous formulations.
Safety
Safety Profile
While 'Garcinia Mangostana Bark Extract' has not been explicitly reviewed by the Cosmetic Ingredient Review (CIR), related extracts like 'Garcinia Mangostana Root Extract' and 'Garcinia Mangostana Whole Plant Extract' are on their 2024 Draft Final Priorities List. A public health warning issued by the FDA concerned an *unregistered food supplement* and does not pertain to the safety of this bark extract as a cosmetic ingredient. INCI Beauty indicates 'no penalty' for this ingredient, suggesting a generally good safety profile in cosmetic use. Oral toxicity studies in mice are not directly translatable to topical cosmetic safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Garcinia Mangostana Bark Extract is a valuable, multifunctional ingredient for addressing various skin concerns, offering antioxidant protection, soothing inflammation, and promoting overall skin health with a low risk of irritation and comedogenicity.
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