Science
Mechanism of Action
This ingredient primarily functions by imparting a pleasant sweet, fruity fragrance to cosmetic products. In formulation, it acts as a solvent, helping to dissolve other components, and as an emulsifier, stabilizing oil-in-water or water-in-oil mixtures. Preliminary data also indicates a potential to contribute to skin hydration.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Gamma-Dodecalactone is predominantly used as a fragrance component rather than a primary active ingredient. Therefore, its efficacy is not typically assessed through 'dusting' thresholds or specific concentration ranges for clinical benefits.
The Formula
Formulation
Stability
Gamma-Dodecalactone demonstrates stability at room temperatures. However, it can undergo hydrolysis when exposed to strong alkaline or strong acid environments. Lactones, including this compound, are known to polymerize over extended periods in alcohol solutions, which may lead to alterations in viscosity or phase separation.
Conflicts
- strong acids
- strong alkalis
Safety
Safety Profile
The Expert Panel for Fragrance Safety (RIFM) has deemed this material safe for use as described in their assessment. Human maximization tests showed no skin sensitization reactions at concentrations up to 12% γ-dodecalactone, and it is not expected to be phototoxic or photoallergenic. The IFRA (51st Amendment) does not restrict this ingredient, permitting usage up to 100% in finished products, although typical fragrance concentrates often use up to 12%. It is important to note that GHS classification lists it as a Skin Irritant Category 2 and Eye Irritant Category 2A, with historical descriptions indicating potential irritation to skin and eyes (Xi - Irritant, R 36/38). The FDA has designated it as safe for general or specific limited use as a synthetic flavoring substance in food.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Gamma-Dodecalactone serves as an effective fragrance agent, offering a pleasant fruity scent with ancillary benefits as a solvent and emulsifier, demonstrating low irritancy and comedogenicity in cosmetic applications despite specific hazard classifications.
Related
Similar Ingredients
Finding similar ingredients…