Science
Mechanism of Action
Galloyl Tetrapeptide-19, a conjugate of gallic acid and tetrapeptide-19, functions as an antioxidant and skin protective agent. Its mechanism involves signaling the body to activate endogenous skin repair processes, leading to anti-aging effects such as enhanced regeneration, structural strengthening, and visible wrinkle reduction, thereby improving skin complexion and elasticity. Studies on structurally related galloyl-peptides have further revealed capabilities in free radical scavenging, mitochondrial activation, increased expression of type I collagen, and inhibition of elastase and MMP-1 enzymes.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Direct safety assessments from CIR, SCCS, or FDA for GALLOYL TETRAPEPTIDE-19 are not available. However, studies on related galloyl-peptides suggest a favorable safety profile. For instance, 'Galloyl-RGD' demonstrated high HaCaT keratinocyte viability (99.56% at 100 ppm and 93.53% at 500 ppm). Another related formulation, '(galloyl)2–KTPPTTP', showed no cytotoxicity in skin cells, with an 88% cell survival rate for keratinocytes and fibroblasts below 100 μM.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While related peptides demonstrate promising antioxidant and anti-aging effects, direct clinical and safety data for GALLOYL TETRAPEPTIDE-19 are currently insufficient to provide a definitive efficacy and safety verdict.
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