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GALLIC ACID.

Valuable CAS 149-91-7 / ANTIOXIDANT

Gallic acid is a potent plant-derived polyphenol, recognized for its multifaceted benefits in skincare. It acts as a powerful antioxidant, effectively neutralizing free radicals, while also exhibiting significant anti-inflammatory and antimelanogenic properties to soothe skin and reduce hyperpigmentation.

Antioxidant Skin-soothing Anti-inflammatory Antimicrobial Sebum-regulating Collagen-boosting Antimelanogenic Brightening

Science

Gallic acid functions primarily as a robust antioxidant, actively scavenging harmful free radicals and offering protection against environmental stressors, with some research suggesting a potency potentially surpassing that of vitamin C. It mitigates inflammation, thereby calming redness, reducing swelling, and assisting in the amelioration of post-inflammatory dark spots. Furthermore, it demonstrates antimicrobial efficacy against acne-causing bacteria and regulates sebum production, rendering it beneficial for managing oily and acne-prone skin conditions. Beyond these actions, gallic acid supports collagen synthesis, contributing to improved skin firmness, elasticity, and a reduction in the appearance of fine lines. It also possesses antimelanogenic effects, inhibiting melanin synthesis to effectively reduce hyperpigmentation.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Gallic acid is susceptible to environmental degradation, with solutions, particularly alkali metal salts, absorbing oxygen and browning in air, indicating oxidative instability in alkaline environments. Its antioxidant capacity is maximized at an acidic pH, specifically pH 2. However, its methylglyoxal-trapping efficiency increases at a higher pH range of 6.5 to 8.0. For applications requiring higher concentrations and enhanced bioavailability, nanoformulations may be advantageous due to its relatively poorer water solubility in such contexts.

Conflicts

  • Potentially irritating ingredients such as retinoids and other skincare acids due to an increased risk of irritation when combined on skin.

Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for use in skincare and holds a US FDA GRAS (Generally Recognized As Safe) status. While its derivative, Propyl Gallate, has been reviewed by CIR and found safe below 0.1%, Gallic Acid itself lacks a dedicated CIR safety assessment with a specified maximum concentration. Concentrated forms are classified as causing skin and serious eye irritation, with few reported cases of gallate-induced skin allergies.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Gallic acid is a valuable ingredient, offering broad-spectrum benefits including antioxidant protection, anti-inflammatory action, and support for collagen and melanin regulation, making it suitable for a wide range of skin concerns.


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