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Moumoujus

GALLA RHOIS GALLNUT EXTRACT.

Valuable CAS - / ANTIMICROBIAL, ANTIOXIDANT

Derived from the gallnuts of Rhus javanica, Galla Rhois Gallnut Extract is a botanical powerhouse, rich in tannins like gallic and ellagic acids. It offers comprehensive benefits for skin, ranging from antioxidant protection and anti-aging effects to skin brightening and soothing properties.

Summary

Antioxidant Anti-aging Skin Brightening Astringent Anti-inflammatory Antimicrobial Skin-conditioning Soothing

Science

Mechanism of Action

This extract combats premature aging by neutralizing free radicals, inhibiting matrix metalloproteinases (MMPs), collagenases, and elastases, and promoting collagen and hyaluronan synthesis. Its high tannin content provides astringent action, minimizing pores and controlling oil. Skin brightening is achieved through tyrosinase inhibition, reducing hyperpigmentation. Furthermore, it possesses anti-inflammatory and antimicrobial properties, helping to calm irritation and maintain skin health.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–5%
Optimal

N/A

Key findings

  1. 01 Clinical studies utilizing a nanoemulsion form (PolyWhitenyl) demonstrated improvement in skin tone.
  2. 02 In vitro testing revealed over 40% inhibition of elastase activity and superior anti-tyrosinase activity compared to arbutin, indicating significant anti-aging and skin brightening potential.

Transparency

Dusting Analysis

Not commonly dusted

Galla Rhois Gallnut Extract provides a broad spectrum of clinically supported and mechanistically sound benefits, making it a valuable active ingredient rather than one typically used at sub-efficacious 'dusting' levels.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Extracted tannins are sensitive to heat, UV radiation, and high (alkaline) pH, which can lead to chemical degradation. Stability is generally optimized in acidic to neutral conditions (e.g., pH 2.5 for total phenolics, pH 6.2 for lignans, and pH 7 for certain pigment solutions).

Conflicts

  • High pH (alkaline conditions) can cause degradation.
  • Iron can lead to undesirable color changes (e.g., greys, blacks, deep eggplant purples).
  • Strong negative charges may require dosage adjustments or dilution, particularly for nanoemulsion forms.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The CIR Expert Panel has not specifically reviewed Galla Rhois Gallnut Extract. While a nanoemulsion product containing it used FDA GRAS class materials for its components, this does not confer general FDA cosmetic status on the extract itself. SkinSAFE categorizes it as 'Teen SAFE', 'Talc Free', 'Lip SAFE', 'Baby SAFE', and 'Eyelid SAFE', free from common allergens. However, a patch test is recommended due to potential irritation, and individuals allergic to sumac or cashews may experience allergenicity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Galla Rhois Gallnut Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-aging, and skin tone-improving benefits, making it suitable for a wide range of precision skincare formulations.

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