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FRUCTOOLIGOSACCHARIDE CAPRYLATE.

Valuable / SKIN CONDITIONING

Fructooligosaccharide Caprylate is a multi-functional ester combining prebiotic fructooligosaccharides (FOS) with a caprylate fatty acid. This unique blend conditions the skin, enhances hydration, and supports a balanced skin microbiome while acting as an emollient to improve skin texture and strengthen the barrier.

Summary

skin conditioning emollient humectant prebiotic antioxidant antimicrobial anti-inflammatory barrier support

Science

Mechanism of Action

This ingredient operates through a dual mechanism. Its fructooligosaccharide (FOS) component functions as a prebiotic, selectively nourishing beneficial skin bacteria to foster a balanced microbiome. This activity is crucial for enhancing skin hydration, reinforcing natural defenses, and bolstering barrier function. FOS also exhibits potential antioxidant properties. Concurrently, the caprylate portion, similar to Coco-Caprylate or Caprylic/Capric Triglyceride, acts as an effective emollient, imparting a smooth, silky feel to the skin. It aids in preventing transepidermal moisture loss and further strengthens the skin's natural barrier, alongside contributing anti-inflammatory, antimicrobial, and antifungal benefits.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application of Fructooligosaccharides (FOS) has demonstrated efficacy in alleviating atopic dermatitis symptoms and enhancing skin hydration, attributed to promoting beneficial skin bacteria and supporting barrier function.
  2. 02 An in vitro study revealed that a 2% FOS fermentation supernatant significantly inhibited Staphylococcus aureus biofilm formation, indicating potential antimicrobial activity against problematic skin bacteria.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 5.5 – 7
0 7 14

Stability

The fructooligosaccharide (FOS) component is sensitive to hydrolysis and degradation in highly acidic environments, particularly below pH 4.0, with elevated temperatures accelerating this process. Optimal stability for FOS is observed within the pH range of 5.5 to 7.0, specifically 5.5-6.0 for enzyme activity. Long-term storage in acidic liquid formulations can lead to a significant reduction in FOS concentration. High-concentration FOS syrups may also exhibit crystallization or cloudiness at room or low temperatures, especially when formulated with high levels of sugar or monosaccharides.

Conflicts

  • Highly acidic environments (below pH 4.0) due to FOS instability and degradation.
  • High concentrations of sugar or monosaccharides in liquid forms, which can lead to crystallization or cloudiness.

Safety

Safety Profile

CIR Status
Unknown
Sensitization risk Low

No specific Cosmetic Ingredient Review (CIR) safety assessment for 'Fructooligosaccharide Caprylate' has been published. However, Fructooligosaccharides (FOS) are broadly recognized as safe for cosmetic use without concentration restrictions and hold FDA's Generally Recognized As Safe (GRAS) status for food applications up to 6.7% or 20g/day. Caprylates, such as Caprylic/Capric Triglyceride, are generally well-tolerated across most skin types. The FDA allows the use of any safe cosmetic ingredient, excluding color additives.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Fructooligosaccharide Caprylate is a valuable, multi-functional ingredient that leverages prebiotic and emollient properties to enhance skin hydration, balance the microbiome, strengthen the skin barrier, and soothe inflammation, with a low risk of irritation or comedogenicity.

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