Science
Mechanism of Action
Fragaria Ananassa Calyx Extract exerts its beneficial effects through several distinct mechanisms. Its abundance of polyphenols, anthocyanins, and vitamins equips the skin with robust antioxidant defense, neutralizing free radicals. Anti-inflammatory actions are observed via the inhibition of the MAPK and NF-κB signaling pathways. The extract also refines complexion by toning the skin's micro-vessels, which promotes superior cellular oxygenation for a regenerated, fresher appearance. An astringent effect, attributed to its tannin content, helps to refine skin texture and reduce pore diameter. Furthermore, its anti-tyrosinase properties, particularly from compounds like ellagic acid, interrupt melanin formation pathways, leading to a brighter and more even skin tone. This extract additionally supports skin barrier integrity and natural cellular regeneration.
Research
Clinical Evidence
Medium confidence0.0025%
Key findings
- 01 At a concentration of 0.0025% (25 μg/mL), notable photoprotection was observed in human dermal fibroblasts (HuDe) when exposed to UVA radiation, demonstrating an increase in cell viability in a dose-dependent manner.
- 02 Anti-inflammatory activity was identified through the inhibition of the MAPK and NF-κB signaling pathways.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Fragaria Ananassa Calyx Extract is sensitive to environmental factors. Exposure to elevated temperatures (e.g., 40°C) can result in darkening and increased fluidity, while light exposure may cause a brownish-green discoloration due to oxidative processes. Optimal stability is achieved with storage in cool, dark conditions and formulation within opaque packaging.
Safety
Safety Profile
While Fragaria Ananassa Calyx Extract itself has not undergone specific review by CIR, related Fragaria ananassa folium (leaf) has been deemed safe (Class 1) by the European Union herbal monograph (EMA/HMPC), with no clinically-relevant interactions expected (Class A). General strawberry extracts are broadly recognized as safe for cosmetic applications by regulatory bodies like the European Cosmetics Regulation. However, as with any natural ingredient, some individuals, particularly those with sensitive skin, may experience allergic reactions or sensitivity, manifesting as itching or rash; thus, patch testing is recommended for this demographic.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Fragaria Ananassa Calyx Extract is a valuable botanical ingredient, offering comprehensive benefits including antioxidant defense, anti-inflammatory action, photoprotection, and skin tone refinement for a revitalized complexion.
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