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Moumoujus

FOENICULUM VULGARE VULGARE FRUIT EXTRACT.

Valuable CAS 92623-75-1 / PERFUMING

Foeniculum Vulgare Vulgare Fruit Extract, derived from the fennel fruit, is a versatile botanical ingredient recognized for its robust antioxidant and anti-inflammatory properties. It actively defends skin from environmental aggressors, mitigates irritation, and supports an even, more radiant complexion through its anti-melanogenic and anti-aging actions.

Summary

Antioxidant Skin-soothing Anti-inflammatory Anti-aging Moisturizing Antimicrobial Antiseptic Toning Firming Promotes circulation Inhibits melanogenesis Perfuming

Science

Mechanism of Action

This extract acts as a potent antioxidant by actively scavenging free radicals and safeguarding skin cells from oxidative damage. Its anti-inflammatory and soothing properties are evident through its ability to inhibit protein denaturation and stabilize cell membranes, which contributes to calming irritation and a mild antiseptic effect. It promotes anti-aging by stimulating collagen synthesis, thereby helping to reduce the appearance of fine lines and wrinkles for firmer, more regenerated skin. The extract also enhances skin hydration by supporting its natural moisture barrier and exhibits antimicrobial qualities that help eliminate bacteria and impurities. Furthermore, it tones and firms the skin, improving elasticity and smoothness, and boosts microcirculation to enhance nutrient delivery and oxygenation to sub-dermal tissues. Research indicates its capacity to inhibit UV-induced melanogenesis by blocking ORAI1 ion channels. Its active composition includes vitamins A, B, C, essential oils, flavonoids, and phenolic acids.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–0.02%
Optimal

N/A

Key findings

  1. 01 Water and ethanol extracts of F. vulgare seeds, at 100 μg (0.01%), exhibited 99.1% and 77.5% inhibition of peroxidation in a linoleic acid system, respectively, demonstrating superior antioxidant activity compared to α-tocopherol (36.1%).
  2. 02 A hydromethanolic extract of Foeniculum vulgare seeds demonstrated maximum protein denaturation inhibition of 35.68±0.40% at 200 μg/mL (0.02%).
  3. 03 The hydromethanolic extract of Foeniculum vulgare seeds showed a maximum inhibition of 9.67±0.30% in heat-induced hemolysis at 200 μg/mL (0.02%), indicating cell membrane stabilization.
  4. 04 Foeniculum vulgare fruit extract significantly inhibited UV-induced melanogenesis and tyrosinase activity by strongly blocking ORAI1 currents in melanoma cells. Its constituent, trans-anethole, inhibited ORAI1 with an IC50 of 8.954±1.36μM.

Transparency

Dusting Analysis

Not commonly dusted

The provided research data does not contain specific information regarding dusting practices or thresholds for Foeniculum Vulgare Vulgare Fruit Extract in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific stability considerations were not detailed in the provided data.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The U.S. Food and Drug Administration (FDA) designates Foeniculum Vulgare (Fennel) Fruit Extract as safe for general or specific, limited use in food. The European Chemicals Agency (ECHA) reports limited evidence of dermal toxicity or allergies. EWG Skin Deep rates this ingredient as 'LOW' concern across various health aspects. An aqueous extract of fennel is noted to be free from essential oils and common fragrance allergens, and it exhibits a mild antiseptic effect, making it potentially beneficial for sensitive skin.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Foeniculum Vulgare Vulgare Fruit Extract is a valuable botanical ingredient, offering significant antioxidant, anti-inflammatory, and anti-melanogenic benefits, making it suitable for a wide range of skin types seeking protection and rejuvenation.

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