Science
Mechanism of Action
This extract supports skin health through multiple distinct mechanisms. It acts as a potent antioxidant, primarily due to its rich content of polyphenolic compounds, including rutin and quercetin-3-galactoside, which effectively scavenge and neutralize damaging free radicals. Concurrently, it exhibits anti-inflammatory capabilities, providing a soothing effect and aiding in the reduction of skin irritation. The extract also demonstrates broad-spectrum antimicrobial activity, inhibiting bacterial and fungal growth, disrupting bacterial biofilm formation, and mitigating hemolytic activity. These integrated actions contribute to skin protection, promote healing, and alleviate symptoms of various skin conditions.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Methanolic stem bark extract exhibited significant free radical scavenging activity (DPPH) with an IC50 of 19 µg/ml.
- 02 Aqueous stem bark extract demonstrated significant inhibition of lipid peroxidation with an IC50 of 80.24 µg/ml.
- 03 Aqueous root extract achieved 96.07% DPPH radical scavenging activity.
- 04 Methanolic extracts inhibited a range of bacterial and fungal strains.
- 05 Methanolic bark extracts showed remarkable activity against enterotoxigenic E. coli.
- 06 Methanolic bark extract decreased Methicillin-resistant Staphylococcus aureus (MRSA) survival by 75.30% at 25 mg/mL, and effectively reduced MRSA biofilm formation and hemolytic activity.
- 07 Methanolic bark extract demonstrated a Minimum Inhibitory Concentration (MIC) of 50 mg/ml and a Minimum Bactericidal Concentration (MBC) of 100 mg/ml against MRSA.
Transparency
Dusting Analysis
No specific data available on dusting for this ingredient in cosmetic formulations.
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not yet reviewed this ingredient for safety. The Environmental Working Group (EWG) reports 'No Data' concerning skin allergies & irritation, developmental & reproductive toxicity, or carcinogenic potential.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ficus Benghalensis Bark/Bud Extract is a valuable botanical ingredient offering comprehensive antioxidant, anti-inflammatory, and antimicrobial benefits, making it suitable across all skin types for supporting overall skin health and resilience.
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