Science
Mechanism of Action
This extract functions as a powerful antioxidant by actively eliminating free radicals, thereby shielding the skin from environmental stressors and decelerating the aging process. It robustly stimulates both the production and secretion of collagen from fibroblasts, which significantly enhances skin elasticity and reduces the appearance of wrinkles. Furthermore, Fertilized Roe Extract exhibits anti-inflammatory properties, effectively diminishing redness, and inhibits tyrosinase activity to contribute to a more uniform skin tone. Its multifaceted components also facilitate enzymatic exfoliation of dead skin cells, encourage new cell growth, act as a humectant to retain moisture, increase fibroblast cell proliferation, improve skin lucidity, and help regulate sebum content.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 At 0.0125% concentration, in vitro studies demonstrated significant antioxidant activity via free radical elimination and inhibition of tyrosinase activity in mouse melanoma cell lines.
- 02 In a double-blinded, randomized clinical trial on human facial skin, topical application of salmon egg extract (1% and 5%) significantly improved wrinkles, pigmentation, redness, brightness, and hydration in a dose- and time-dependent manner, with no adverse reactions reported.
- 03 A 5% fertilized salmon egg extract in a serum base significantly decreased surface roughness and fine lines over control at day 7, 14, and 28. It also significantly reduced melanin and redness, improved skin lucidity, increased skin water content, and decreased sebum content.
- 04 A 1% fertilized salmon egg extract in a serum base had a significant effect on surface roughness and fine lines over control at day 7.
- 05 Human dermal fibroblast cultures treated with high and low concentrations of chum salmon egg extracts showed a concentration-dependent upregulation of collagen type I genes and multiple antioxidative genes (OXR1, TXNRD1, PRDX family genes).
- 06 Salmon Roe Extract (1-5%) has been associated with reductions in crow's feet and wrinkles by up to 32%, increases in collagen secretion by up to 350% and elastin by up to 120%, and a reduction in redness and inflammation by up to 21%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
An antioxidant protein derived from fertilized eggs demonstrates stability in acidic to neutral pH environments (below 7) and at temperatures ranging from 30-50°C. Compositions utilizing fish egg cellular extract have been effectively formulated within a pH range of 5.0 to 7.7.
Safety
Safety Profile
While human clinical trials on 'Salmon egg extract' have reported no adverse reactions, skin irritation, or sensitization, 'FERTILIZED ROE EXTRACT' specifically does not have a dedicated CIR (Cosmetic Ingredient Review) report. In the US, cosmetic ingredients, excluding color additives and certain prohibited substances, generally do not require pre-market FDA approval.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Fertilized Roe Extract is a valuable, multi-functional ingredient clinically demonstrated to significantly improve visible signs of aging, enhance hydration, brighten skin tone, and reduce inflammation across all skin types.
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References
Sources