Science
Mechanism of Action
Fabiana Imbricata Oil primarily acts by inhibiting protein denaturation, a key process linked to inflammatory responses, thereby exerting anti-inflammatory effects. Its composition includes polyphenolic compounds such as alkaloids, flavonoids, tannins, steroids, and phenols, which are believed to provide antioxidant activity by scavenging free radicals. This multifaceted action allows it to soothe skin and address cutaneous disorders with an inflammatory component.
Research
Clinical Evidence
Medium confidence0.1-1.0%
Key findings
- 01 An ethanolic extract demonstrated significant anti-inflammatory activity in vitro, inhibiting heat-induced albumin denaturation by 71% at a concentration of 0.05% (500 µg/mL).
- 02 The essential oil is effectively utilized as a soothing agent to prevent and treat skin discomforts such as redness, itching, and various inflammatory conditions. Optimal cosmetic concentrations are typically between 0.1% and 1.0%, though effective ranges extend from 0.01% to 5.0% for cosmetic applications.
Transparency
Dusting Analysis
Information regarding the 'dusting' of Fabiana Imbricata Oil is not available in the provided research data, indicating it is not a common practice or concern for this ingredient.
The Formula
Formulation
Stability
Fabiana Imbricata Oil, typically obtained via steam extraction as an essential oil, is soluble in alcohol but insoluble in water. Historical references to infusions suggest precipitation in water unless alkalinized, but this characteristic does not apply to the isolated oil itself.
Safety
Safety Profile
While no specific CIR review exists for Fabiana Imbricata Oil, the CIR Expert Panel has generally deemed 244 plant-derived fatty acid oils safe for cosmetic use. Acute oral toxicity studies in rats and mice using crude F. imbricata extract (1.0 and 5.0 g/kg) showed no adverse behavioral changes or organ damage. In vitro tests (0.10–0.50 mg/mL extract) did not induce chromosome damage in human lymphocytes. It is regarded as a safe crude drug in traditional medicine, with The Good Scents Company reporting no GHS classification, hazard statements, or determined toxicity data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Fabiana Imbricata Oil is a valuable ingredient for precision skincare, offering significant anti-inflammatory and antioxidant benefits, particularly effective for soothing sensitive or inflamed skin.
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