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Moumoujus

FABIANA IMBRICATA LEAF/STEM EXTRACT.

Valuable CAS 90028-69-6 / SKIN CONDITIONING, TONIC

Fabiana Imbricata Leaf/Stem Extract is a botanical active rich in polyphenolic compounds, offering multifaceted benefits for skin health. It demonstrates in vitro potential in modulating inflammation, combating oxidative stress, regulating sebum production, and mitigating visible signs of aging.

Summary

Skin Conditioning Tonic Anti-inflammatory Antioxidant Anti-aging Sebum Control Biofilm Inhibition

Science

Mechanism of Action

This extract functions as an anti-inflammatory agent by inhibiting protein denaturation, a key pathway in inflammatory responses. Its comprehensive profile of polyphenolic compounds, including alkaloids, flavonoids, tannins, steroids, and phenols, provides significant antioxidant protection by neutralizing free radicals and acting as primary oxidants. Furthermore, it can modulate sebum production through the inhibition of lipoxygenase activity, making it beneficial for oily skin conditions. The extract also contributes to anti-aging by inhibiting MMP-1 activity, which can reduce the appearance of fine lines, wrinkles, and skin laxity, in addition to reducing oxidative cellular damage.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibited heat-induced albumin denaturation by 71%, demonstrating anti-inflammatory activity.
  2. 02 Inhibited biofilm formation by 78% and reduced metabolic activity by 67%.
  3. 03 Essential oil of Fabiana imbricata cited for soothing properties, preventing and/or treating skin discomfort reactions such as redness, itching, sensations of heat and/or burn, tightness, and gnawing pain.

Transparency

Dusting Analysis

Not commonly dusted

Information regarding dusting practices or specific thresholds for FABIANA IMBRICATA LEAF/STEM EXTRACT is not available in the provided research data.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract's diverse chemical composition suggests a dual solubility profile, with polar compounds like polyphenols showing water solubility and non-polar triterpenes exhibiting oil solubility. The plant's resin is noted to be water-resistant, and alcohol tinctures may precipitate when added to water, indicating some components are alcohol-soluble.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed FABIANA IMBRICATA LEAF/STEM EXTRACT. In vitro studies have indicated low toxicity for crude drug extracts, showing no clastogenic effect in human lymphocytes at concentrations ranging from 0.10–0.50 mg/mL, suggesting a favorable preliminary safety profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Fabiana Imbricata Leaf/Stem Extract is a valuable botanical ingredient, demonstrating promising in vitro anti-inflammatory, antioxidant, and anti-aging benefits, alongside potential for sebum control, warranting its inclusion in advanced skincare formulations.

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