Science
Mechanism of Action
This extract exerts its dermatological effects through multiple mechanisms. Its robust antioxidant capacity is attributed to compounds such as scopoletin and flavonoids, which effectively neutralize oxidative stress and prevent lipid peroxidation. Anti-inflammatory actions are observed by reducing inflammatory responses, as evidenced by suppressed paw edema in rats. Furthermore, it supports skin regeneration by increasing fibroblast activity and collagen density, crucial for tissue repair. Its broad-spectrum efficacy extends to antimicrobial, antibacterial, and antifungal activities against a range of pathogens, contributing to skin health and protection.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
There is no available information to suggest this ingredient is commonly used in 'dusted' formulations or presents associated red flags.
The Formula
Formulation
Stability
A formulated aqueous cream containing Evolvulus Alsinoides extract was found to be stable, homogeneous, and exhibited good consistency at a pH of 5.58, indicating favorable stability within cosmetic formulations.
Safety
Safety Profile
Oral toxicity studies in mice, even at high doses of ethanolic extracts up to 2000 mg/kg, demonstrated no mortality or significant adverse toxicological effects. Compounds within methanolic extracts have been described as non-toxic. Crucially for topical application, a formulated cream containing the aqueous extract was specifically reported not to cause skin irritation. While traditional oral uses of concentrated extracts may lead to gastrointestinal upset or hypotension, these effects are not relevant for cosmetic topical application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Evolvulus Alsinoides Flower/Leaf/Stem Extract is a valuable botanical ingredient, presenting significant antioxidant, anti-inflammatory, and wound-healing benefits with a favorable low risk of skin irritation for topical applications.
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References
Sources