Science
Mechanism of Action
The extract functions as a potent antioxidant by inhibiting oxygen-favored reactions and actively scavenging free radicals. Its skin-brightening efficacy stems from significantly reducing tyrosinase activity, decreasing melanin content, and downregulating α-MSH-induced expression of tyrosinase and microphthalmia-associated transcription factor (MITF). Furthermore, it exhibits antimicrobial properties, specifically inhibiting *Propionibacterium acnes*, and pronounced anti-inflammatory effects attributed to its flavonoid and triterpene content, which includes β-amyrin, and by blocking NADPH oxidase (NOX) activation to protect keratinocytes from pollutant-induced damage. The extract also possesses astringent qualities, contributing to refined skin pores.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Extracts are commonly prepared using 70% ethanol or 85% aqueous methanol, indicating optimal solubility and stability within hydro-alcoholic solvent systems.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically evaluated Euphorbia Supina Leaf/Stem Extract. However, INCI Beauty indicates 'No penalty' across all safety categories for EUPHORBIA SUPINA STEM EXTRACT, suggesting a favorable safety profile. While some *Euphorbia* species contain irritating latex, this caution is generalized and not specifically linked to the prepared leaf/stem extract for cosmetic use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Euphorbia Supina Leaf/Stem Extract is a valuable botanical ingredient, offering comprehensive benefits including brightening, antioxidant, anti-inflammatory, and antimicrobial actions, making it suitable for a wide range of skin types and concerns.
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