Science
Mechanism of Action
The mechanism of EUGLENA/OLEIC ACID FERMENT is multi-faceted. Euglena extracts are observed to bolster skin barrier function, enhance hydration, mitigate oxidative stress, and stimulate the in vitro production of vital proteins like collagen and elastin in human skin cells. These extracts also exhibit anti-inflammatory and antioxidant activities, while activating skin immune cells to foster hyaluronic acid synthesis, which contributes to skin firmness and elasticity. Oleic Acid functions as a potent permeation and penetration enhancer, modifying skin barrier lipids to improve the absorption of other active compounds. Furthermore, it acts as an emollient, supplementing the skin's natural lipid barrier. The fermentation process itself contributes by breaking down complex substances into smaller, more absorbable molecules and potentially reducing undesirable compounds, thereby enhancing both efficacy and tolerability.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Euglena gracilis extracts at concentrations as low as 0.1 µg/mL significantly reduced TNF-α production, demonstrating anti-inflammatory effects.
- 02 Anti-inflammatory and antioxidant activities were maintained at low Euglena gracilis extract concentrations (<10 µg/mL), increasing intracellular reducing potential.
- 03 Laboratory and limited clinical studies indicate Euglena extracts can enhance skin barrier function, promote hydration, reduce oxidative stress, and stimulate collagen and elastin synthesis in human skin cells in vitro.
- 04 Euglena extract is believed to activate skin immune cells and promote hyaluronic acid synthesis, leading to improved moisturizing power, firmness, and elasticity.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The stability of EUGLENA/OLEIC ACID FERMENT is likely optimized within a pH range of 5.0 to 7.0, consistent with common microalgae fermentation processes for high-oleic acid oil. Euglena fermentation itself has been studied across a broader pH spectrum (3-8), often thriving in slightly acidic conditions around pH 3.5. Careful formulation within the recommended optimal range is crucial to maintain the active compounds' integrity and efficacy.
Safety
Safety Profile
The specific ingredient EUGLENA/OLEIC ACID FERMENT has not undergone individual safety assessment by CIR or SCCS. However, Oleic Acid, a key component, has been reviewed by CIR within broader assessments of fatty acids and is affirmed as Generally Recognized As Safe (GRAS) by the FDA when migrating from food packaging. Safety data for yeast-derived ferments, a related category, varies, with some considered safe and others requiring further data. Given the lack of specific data for this combined ferment, its sensitization risk remains unknown.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ferment offers a valuable array of benefits, leveraging Euglena's cellular regenerative properties and Oleic Acid's barrier and delivery enhancement, though further specific clinical data on the combined ferment is needed.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources