Science
Mechanism of Action
Euglena Gracilis Polysaccharide, primarily paramylon, operates through several pathways to improve skin health. It strengthens the skin's natural barrier function and boosts hydration. Mechanistically, it promotes the in vitro production of vital skin proteins like collagen and elastin, while also offering antioxidant protection by increasing intracellular GSH levels and mitigating reactive oxygen species (ROS) production. Its anti-inflammatory capabilities involve reducing pro-inflammatory cytokines such as TNF-α, contributing to a calmer, more resilient complexion and supporting cellular metabolism. It also aids in wound healing by facilitating re-epithelization.
Research
Clinical Evidence
Medium confidence3%
Key findings
- 01 A 14-day study demonstrated that a 3% aqueous extract of Euglena gracilis significantly improved cutaneous vitality and decreased skin deformability.
- 02 In animal models, both live Euglena gracilis cells and their aqueous extract were shown to facilitate wound healing, promoting re-epithelization and reducing excessive scarring without inducing inflammatory responses.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While its primary component, paramylon, is inherently water-insoluble, Euglena Gracilis Polysaccharide is formulated for water dispersibility or used in modified, water-soluble forms (e.g., carboxymethylated paramylon) for effective integration into cosmetic systems, where it also functions as a gel-forming and viscosity-controlling agent.
Safety
Safety Profile
The parent organism, Euglena gracilis, has received 'Self-determined GRAS' (Generally Recognized As Safe) status in the United States for food applications, suggesting a favorable safety profile; however, specific Cosmetic Ingredient Review (CIR) assessment for skin use is pending.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Euglena Gracilis Polysaccharide is a valuable multi-functional ingredient that enhances skin hydration, barrier function, and anti-aging defenses, making it suitable for a wide range of skin types.
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References
Sources