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Moumoujus

EUGLENA GRACILIS EXTRACT.

Valuable / SKIN CONDITIONING

Euglena Gracilis Extract is a unique microalgae derivative rich in polysaccharides, vitamins, and amino acids. It functions as a multifaceted skin conditioner, enhancing hydration, supporting the skin barrier, and providing antioxidant protection. This extract revitalizes skin by stimulating cellular metabolism and key structural proteins.

Summary

Emollient Skin-conditioning Antioxidant Hydration Anti-inflammatory Collagen Stimulator Elastin Stimulator Cellular Energizer Cell Renewal Barrier Support

Science

Mechanism of Action

This extract leverages bioactive compounds, including paramylon polysaccharides, vitamins, and minerals, to fortify the skin. It notably boosts ATP synthesis and cellular metabolism via phosphoinositides, leading to enhanced skin energy and renewal. It also stimulates collagen and elastin production, contributing to improved skin elasticity, and provides significant anti-inflammatory and antioxidant benefits by reducing pro-inflammatory mediators and increasing cellular reducing potential. These actions collectively support barrier function, hydration, and overall skin vitality.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

3%

Key findings

  1. 01 3% concentration significantly increased cutaneous vitality and decreased skin deformability after 14 days of treatment.
  2. 02 An aqueous extract facilitated wound healing in mice by promoting re-epithelization without inducing excessive inflammation.
  3. 03 In vitro, concentrations from 0.1 µg/mL to 10 µg/mL demonstrated anti-inflammatory effects by reducing TNF-α production and antioxidant activity by increasing GSH levels in human macrophages.
  4. 04 At 10 µg/mL and higher, it blocked LPS-induced nitrite release and downregulated pro-inflammatory mediators via NF-κB and Nrf2 pathways in microglia, exhibiting non-cytotoxic effects up to 100 µg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 7.5
0 7 14

Stability

The extract is derived from Euglena gracilis, which thrives in a pH range of 3.5-7.5, with optimal protein production noted at pH 3.5 and cultures typically maintained around pH 6.8. While direct cosmetic formulation stability data is not extensively detailed, maintaining an acidic to neutral pH environment is inferred to support extract integrity and activity.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) and Scientific Committee on Consumer Safety (SCCS) have not evaluated Euglena Gracilis Extract. However, the dried whole cell has Qualified Presumption of Safety (QPS) status by EFSA for food applications, with a NOAEL of 3,300 mg/kg body weight. In vitro studies show non-cytotoxic effects up to 100 µg/mL, and the EWG Skin Deep database indicates low concerns for various toxicities and restrictions, further supporting its safety profile for topical use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Euglena Gracilis Extract is a valuable ingredient, offering broad benefits for skin vitality, hydration, and resilience, suitable for all skin types with a low risk of irritation.

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