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EUGENYL PHENYLACETATE.

Insufficient Data CAS 10402-33-2 / PERFUMING

Eugenyl Phenylacetate is a synthetic ester primarily utilized in cosmetic formulations for its aromatic properties. It enhances the scent of products and can impart fragrance to the skin, serving exclusively as a perfuming agent.

Perfuming Agent

Science

This compound acts as a fragrance enhancer, contributing to the overall scent profile of a cosmetic product or perfuming the skin directly. While its parent compound, eugenol, and other derivatives are generally recognized for antioxidant activity and skin permeation capabilities, direct clinical evidence or a specific mechanism of action demonstrating these benefits for Eugenyl Phenylacetate in skin applications is not currently established.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Eugenyl Phenylacetate is a fragrance ingredient and is not typically associated with overstated or unproven skin benefit claims, thus the concept of 'dusting' does not directly apply.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Eugenyl Phenylacetate exhibits insolubility in water but readily dissolves in alcohol and various oils. As an ester, it may display sensitivity to extreme pH environments, particularly alkaline conditions, similar to observations made for related compounds like Eugenyl Acetate.


Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

The Research Institute for Fragrance Materials (RIFM) has conducted a safety assessment, recommending usage up to 5.0000% in fragrance concentrates. For finished cosmetic products, maximum acceptable concentrations vary by category; for instance, 0.069% in lip products and 1.9% for rinse-off body and hand products. The compound is not anticipated to be genotoxic, and exposure levels fall below the Threshold of Toxicological Concern (TTC) for repeated dose, reproductive, and local respiratory toxicity for a Cramer Class I material. Although specific skin sensitization studies are limited, its chemical structure suggests it is unlikely to directly react with skin proteins. One inconclusive sensitization reaction was noted in 1 of 65 subjects at a high 12% concentration in human maximization tests, potentially due to other materials. Based on existing data and Dermal Sensitisation Threshold (DST) application, it is considered a low concern for skin sensitization at current usage levels. No direct Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) opinion exists for this specific compound, although related eugenol has been reviewed by SCCS.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Eugenyl Phenylacetate serves primarily as a fragrance component in cosmetic products; however, specific clinical data regarding its direct benefits for skin health or function is currently unavailable.


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