Science
Mechanism of Action
This extract functions as a powerful antioxidant by leveraging its rich phenolic compound profile, including gallic acid, ellagic acid, and myricitrin, which effectively scavenge free radicals and mitigate oxidative stress. Its anti-inflammatory action stems from the reduction of inflammatory mediators like TNF-α and IL-1β, alongside the inhibition of key enzymes such as COX-1, COX-2, and 5-LOX. Eugenia Uniflora also exhibits direct antimicrobial effects, including fungicidal and antibacterial activity. Furthermore, it acts as an astringent, promoting skin tightening, and demonstrates anti-aging potential through the inhibition of elastase.
Research
Clinical Evidence
Medium confidence7.81% (topical application in film-forming system)
Transparency
Dusting Analysis
No data suggests this ingredient is commonly dusted.
The Formula
Formulation
Stability
Formulations incorporating Eugenia Uniflora Leaf Extract demonstrate optimal stability and suitability for topical application within a pH range of 4.37 to 5.3.
Synergies
- Tropaeolum majus L. extract (observed enhanced antioxidant and antimicrobial effects in combination)
Safety
Safety Profile
While not formally reviewed by CIR or SCCS, in vivo animal studies of aqueous extracts suggest a high margin of safety, showing non-toxic and non-genotoxic action at oral doses up to 2000 mg/kg. In vitro studies further support its low toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Eugenia Uniflora Leaf Extract is a valuable botanical ingredient, offering a spectrum of benefits including potent antioxidant, anti-inflammatory, antimicrobial, astringent, and anti-aging properties, supported by promising in vitro and initial topical application data.
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References
Sources