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Moumoujus

EUGENIA STIPITATA FRUIT EXTRACT.

Valuable / SKIN CONDITIONING

Eugenia stipitata Fruit Extract is derived from the Amazonian araçá-boi fruit, celebrated for its rich profile of bioactive compounds including phenolics, flavonoids, carotenoids, and vitamin C. This extract offers significant antioxidant and anti-inflammatory benefits, protecting the skin from oxidative damage and supporting overall skin health.

Summary

Antioxidant Skin conditioning Hair conditioning Anti-inflammatory Collagen booster Exfoliant

Science

Mechanism of Action

This extract functions as a potent antioxidant, actively neutralizing free radicals to prevent oxidative stress, lipid peroxidation, DNA damage, and the degradation of vital skin structural proteins. Its robust vitamin C content is crucial for stimulating collagen synthesis, which contributes to enhanced skin firmness and elasticity. Additionally, the extract aids in gentle exfoliation, repair processes, and the rejuvenation of collagen fibers, while compounds like lutein impart anti-inflammatory properties, promoting a calmer complexion.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Ethanolic extract demonstrated significant radical scavenging activity, with an IC50 of 0.69 ± 0.23 μg/mL (DPPH assay, in vitro).
  2. 02 Hydroethanolic extracts from Eugenia stipitata seeds exhibited a high capacity to scavenge DPPH radicals (IC50 46.63 µg/mL, in vitro) and showed no cytotoxicity in blood cells at concentrations up to 1250 µL/mL.
  3. 03 Araçá-boi extract, at concentrations ranging from 200 to 1600 µg/mL, effectively reduced cell viability and inhibited the migration of human metastatic melanoma cells (in vitro).
  4. 04 An ethanolic extract administered orally at 300 mg/kg of body weight demonstrated antimutagenic and antigenotoxic properties in mice, suggesting potential as a cancer preventive agent.

Transparency

Dusting Analysis

Not commonly dusted

No data available to indicate common dusting issues for this ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The fruit pulp from which this extract is derived is naturally highly acidic, with a pH typically ranging from 2.28 to 2.4. This inherent acidity should be considered as it may significantly influence the final pH of formulations containing the extract. While the raw fruit is perishable, specialized extraction methods, such as hydroethanolic solutions, are critical for stabilizing and preserving its bioactive compounds. Heat treatments should be carefully evaluated as they can compromise the extract's composition and stability.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

There is no specific CIR, SCCS, or FDA status for the topical application of Eugenia stipitata Fruit Extract; its classification as 'No Reported Uses' by CIR may suggest a lack of extensive review. However, in vitro studies have indicated low toxicity and no cytotoxic effects on various cell lines or human blood cells, even at elevated concentrations. SkinSAFE additionally lists this ingredient as 'Irritant Free', supporting a low sensitization risk profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Eugenia stipitata Fruit Extract is a valuable ingredient, demonstrating robust antioxidant efficacy and promising benefits for collagen support and inflammation reduction, despite ongoing assessment for comprehensive human topical data.

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