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EUGENIA CUMINI LEAF EXTRACT.

Valuable / SKIN CONDITIONING

EUGENIA CUMINI LEAF EXTRACT, also known as Syzygium cumini leaf extract, is a multi-functional botanical ingredient prized for its rich phenolic and flavonoid content. It offers significant antioxidant, anti-inflammatory, and antimicrobial properties, alongside potential benefits for skin brightening, photoprotection, and wound healing. This extract is a versatile active for comprehensive skin health formulations.

Summary

Antioxidant Anti-inflammatory Antibacterial Antifungal Skin Brightening Photoprotective Wound Healing Astringent Skin Conditioning

Science

Mechanism of Action

This extract exerts its dermatological benefits primarily through its abundant phenolic compounds and flavonoids. As a potent antioxidant, it neutralizes free radicals, thereby mitigating oxidative stress. Its anti-inflammatory action helps to reduce cutaneous irritation and redness. The extract demonstrates broad-spectrum antimicrobial efficacy against various pathogens, including Staphylococcus aureus, Escherichia coli, and Candida albicans, due to its tannin content. For anti-aging and brightening, it inhibits tyrosinase activity to reduce hyperpigmentation and provides photoprotection by scavenging UV-induced free radicals, preventing cellular toxicity in keratinocytes. Its astringent qualities also contribute to balancing oily skin and minimizing acne.

Research

Clinical Evidence

High confidence
Effective range 0.5–1%
Optimal

0.5%

Key findings

  1. 01 Demonstrated antibacterial activity against Gram-positive (Staphylococcus aureus, Candida albicans) and Gram-negative (Escherichia coli) pathogens, and significantly improved topical wound healing in Wistar rats within two weeks.
  2. 02 Exhibited elevated DPPH scavenging activity, indicative of significant antioxidant potential.
  3. 03 Inhibited tyrosinase activity, suggesting potential for reducing hyperpigmentation.
  4. 04 Showed significant photoprotective actions, indicating its potential as a broad-spectrum UV filter.
  5. 05 Demonstrated significant cyto-protective activity in vitro.
  6. 06 Exhibited an inhibitory effect against carrageenan-induced inflammation in preclinical models.

Transparency

Dusting Analysis

Not commonly dusted

Given the broad range of documented biological activities and the nature of this ingredient as a functional extract, it is not commonly considered a 'dusting' ingredient. No specific dusting thresholds or red-flag percentages are available in the research data.

The Formula

Formulation

Solubility
Both
Optimal pH 6.8 – 6.8
0 7 14

Stability

Functional stability for enzyme inhibition assays was observed around pH 6.8 in a potassium phosphate buffer. Topical film-forming solutions incorporating the extract maintained favorable physicochemical properties, including appropriate pH levels and thermal stability, preserving its beneficial characteristics.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No specific CIR or SCCS assessment has been conducted for EUGENIA CUMINI LEAF EXTRACT. While no direct FDA approval for cosmetic use was found, studies generally indicate low to moderate cytotoxicity on human keratinocytes and brine shrimp assays. Extracts are considered non-toxic, with cell viability consistently exceeding 90% at tested concentrations ranging from 0.1 to 250 µg/mL.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

EUGENIA CUMINI LEAF EXTRACT is a multifaceted botanical active offering significant antioxidant, anti-inflammatory, antibacterial, and photoprotective benefits, making it a valuable addition to precision skincare formulations.

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