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ETHYLHEXYL NEOPENTANOATE.

Valuable CAS 16387-18-1 / SKIN CONDITIONING - EMOLLIENT

Ethylhexyl Neopentanoate is a synthetic ester functioning primarily as a skin conditioning agent and emollient. It contributes to enhancing the epidermal barrier by supplying beneficial lipids, thus promoting skin hydration and suppleness.

Skin conditioning Emollient Barrier enhancement Hydration support Transepidermal water loss prevention Inflammation protection

Science

This ingredient works by delivering exogenous lipids to the skin surface, which integrate into the stratum corneum. This action reinforces the natural skin barrier, effectively filling microscopic gaps within intercorneocyte clusters to augment hydration levels and mitigate transepidermal water loss. Furthermore, its barrier-enhancing properties contribute to protection against environmental stressors and support skin's resilience against inflammation.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Ethylhexyl Neopentanoate, as part of a group of alkyl esters, concluding it is safe for use in current cosmetic practices and concentrations, provided formulations are non-irritating. The Environmental Working Group (EWG) Skin Deep database indicates low concern across various toxicity categories, including a low potential for skin, eye, or lung irritation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

As a well-tolerated emollient that directly strengthens the skin barrier and enhances hydration, Ethylhexyl Neopentanoate offers significant value for diverse skincare formulations.


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References