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ETHYL LINOLEATE.

Valuable CAS 544-35-4 / PERFUMING, SKIN CONDITIONING - EMOLLIENT

Ethyl Linoleate is an ethyl ester of linoleic acid, a vital omega-6 polyunsaturated fatty acid. Engineered for superior skin permeability, it delivers comprehensive benefits including hydration, barrier reinforcement, and targeted action against acne and hyperpigmentation.

Emollient Skin Barrier Support Hydrating Anti-inflammatory Antibacterial Sebum Regulating Keratinization Normalizer Anti-Acne Brightening (Pigmentation Reduction) Wound Healing Perfuming

Science

Converted into linoleic acid within the skin, Ethyl Linoleate enhances the skin's lipid barrier, supports ceramide production, and significantly reduces transepidermal water loss, thus boosting hydration. It demonstrates antibacterial and anti-inflammatory effects, aids wound healing, and normalizes follicular keratinization and sebum secretion, making it particularly effective for acne-prone skin. Additionally, it brightens skin by inhibiting melanogenesis through specific signaling pathway downregulation.


Research

High confidence
Effective range 2–10%
Optimal

N/A

Key findings

  1. 01 Effectively used in preparations designed to treat dry, rough, and flaky skin.
  2. 02 Suitable for formulations aimed at maintaining skin hydration and reducing pigmentation.
  3. 03 Reduced inflammatory lesions in mild-to-moderate acne vulgaris when combined with other active agents.
  4. 04 Inhibited the production of pro-inflammatory mediators in sebocytes, suggesting an anti-inflammatory action pertinent to acne pathology.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Stable under normal conditions, but prone to hydrolysis and oxidation when exposed to water, air, heat, or light. For optimal stability, store long-term in a tightly-closed container at 2-8°C, away from incompatible substances and ignition sources.

Synergies

  • Blends well with various oils, esters, silicones, and lipid bases.
  • Acts as an effective solubilizer for hydrophobic active ingredients.

Conflicts

  • water (hydrolysis)
  • air (oxidation)
  • heat (oxidation)
  • light (oxidation)
  • incompatible substances

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

While not specifically assessed by CIR or SCCS, it is 'Generally Recognized As Safe (GRAS)' by the FDA for limited food use. Although GHS reports indicate potential skin irritation in 25.2% of cases, it is generally considered well-tolerated. Topical preparations typically utilize concentrations between 2-10%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Ethyl Linoleate is a valuable multi-functional ingredient that significantly improves skin barrier function, provides deep hydration, reduces inflammation, targets acne, and brightens skin, making it suitable for a broad spectrum of skin concerns.


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